ArticleBMC genomics2007
HYBRIDdb: a database of hybrid genes in the human genome.
Article in BMC genomics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- GraphChrom: A Novel Graph-Based Framework for Cancer Classification Using Chromosomal Rearrangement Endpoints.Cancers · 2022Article
- Clinically relevant fusion oncogenes: detection and practical implications.Therapeutic advances in medical oncology · 2022Review
- ChiTaRS 5.0: the comprehensive database of chimeric transcripts matched with druggable fusions and 3D chromatin maps.Nucleic acids research · 2020Article
- ProtFus: A Comprehensive Method Characterizing Protein-Protein Interactions of Fusion Proteins.PLoS computational biology · 2019Article
- HumCFS: a database of fragile sites in human chromosomes.BMC genomics · 2019Article
- Chimeric RNAs and their implications in cancer.Current opinion in genetics & development · 2018Review
- Discovering and understanding oncogenic gene fusions through data intensive computational approaches.Nucleic acids research · 2016Review
- FusionCancer: a database of cancer fusion genes derived from RNA-seq data.Diagnostic pathology · 2015Article
- FARE-CAFE: a database of functional and regulatory elements of cancer-associated fusion events.Database : the journal of biological databases and curation · 2015Article
- Transcription-mediated chimeric RNAs in prostate cancer: time to revisit old hypothesis?Omics : a journal of integrative biology · 2014Article
- ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data.Nucleic acids research · 2013Article
- dbCRID: a database of chromosomal rearrangements in human diseases.Nucleic acids research · 2011Article
- ChimerDB 2.0--a knowledgebase for fusion genes updated.Nucleic acids research · 2010Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHybrid genes are candidate risk factors for human tumors by inducing mutation, translocation, inversion, or rearrangement of genes. The occurrence of hybrid genes may also have given rise to new transcripts during hominid evolution. DESCRIPTION: HYBRIDdb is a database of hybrid genes in humans. This system encompasses the bioinformatics analysis of mRNA, EST, cDNA, and genomic DNA sequences in the INDC databases, and can be used to identify hybrid genes. We searched for hybrid genes among the 28,171 genes listed in the NCBI database, and analyzed their structural patterns in the human genome. The 2,344 gene pairs were detected as hybrid forms of transcriptional products. We classified the hybrid genes into two groups: chromosomal-mediated translocation fusion transcripts and transcription-mediated fusion transcripts.
conclusionThe HYBRIDdb database will provide genome scientists with insight into potential roles for hybrid genes in human evolution and disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.