ArticleInfection and immunity2007
Biofilms protect Mycoplasma pulmonis cells from lytic effects of complement and gramicidin.
Article in Infection and immunity, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 43 citations in OpenAlex.
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- Research Progress on Immune Evasion ofMicroorganisms · 2024Review
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- Extracellular DNA release from the genome-reduced pathogen Mycoplasma hyopneumoniae is essential for biofilm formation on abiotic surfaces.Scientific reports · 2018Article
- Biofilm formation and determination of minimum biofilm eradication concentration of antibiotics in Mycoplasma hyopneumoniae.The Journal of veterinary medical science · 2017Article
- Antibacterial effects of N-acetylcysteine against endodontic pathogens.Journal of microbiology (Seoul, Korea) · 2016Article
- Catalase Enhances Growth and Biofilm Production of Mycoplasma pneumoniae.Current microbiology · 2015Article
- In vitro effects of N-acetyl cysteine alone and in combination with antibiotics on Prevotella intermedia.Journal of microbiology (Seoul, Korea) · 2015Article
- Biofilm formation avoids complement immunity and phagocytosis of Streptococcus pneumoniae.Infection and immunity · 2013Article
- Role of biofilm formation in Ureaplasma antibiotic susceptibility and development of bronchopulmonary dysplasia in preterm neonates.The Pediatric infectious disease journal · 2013Article
- Type 1 and type 2 strains of Mycoplasma pneumoniae form different biofilms.Microbiology (Reading, England) · 2013Article
- EPS-I polysaccharide protects Mycoplasma pulmonis from phagocytosis.FEMS microbiology letters · 2013Article
- Mycoplasma polysaccharide protects against complement.Microbiology (Reading, England) · 2012Article
- Article
- Nonsex genes in the mating type locus of Candida albicans play roles in a/α biofilm formation, including impermeability and fluconazole resistance.PLoS pathogens · 2012Article
- Mycoplasma biofilms ex vivo and in vivo.FEMS microbiology letters · 2009Article
- Identification of exopolysaccharide-deficient mutants of Mycoplasma pulmonis.Molecular microbiology · 2009Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The length of the tandem repeat region of the Vsa protein of Mycoplasma pulmonis has previously been shown to modulate the susceptibility of mycoplasmas to killing by complement: cells that produce a short form of the Vsa protein are highly sensitive, and cells producing the long Vsa protein are resistant. In contrast to their differing susceptibilities to complement, the mycoplasmas were highly sensitive to gramicidin irrespective of the length of the Vsa protein produced. We show here that when encased within a biofilm, cells of M. pulmonis producing a short form of the Vsa protein were more resistant to complement and gramicidin than mycoplasmas that were dispersed. The resistance appeared to be localized to those mycoplasmas within tower structures of the biofilms. Biofilm formation may be a mechanism that protects mycoplasmas from host immunity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.