ArticleThorax2007
Survival of HIV-infected patients in the intensive care unit in the era of highly active antiretroviral therapy.
Article in Thorax, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed.
- Early antiretroviral therapy for HIV-infected patients admitted to an intensive care unit (EARTH-ICU): A randomized clinical trial.PloS one · 2020Trial
- AIDS but not non-AIDS HIV status is associated with mortality in the intensive care unit.Intensive care medicine · 2024Article
- DNA Methylation Demonstrates Bronchoalveolar Cell Senescence in People Living with HIV: An Observational Cohort Study.Biomedicines · 2024Article
- People living with HIV, HCV and HIV/HCV coinfection in intensive care in a German tertiary referral center 2014-2019.Infection · 2023Article
- Update on the management of patients with HIV infection in anaesthesia and critical care.BJA education · 2023Review
- Risk Factors in HIV-1 Positive Patients on the Intensive Care Unit: A Single Center Experience from a Tertiary Care Hospital.Viruses · 2023Article
- Outcomes in critically Ill HIV-infected patients between 1997 and 2020: analysis of the OUTCOMEREA multicenter cohort.Critical care (London, England) · 2023Article
- Study on Respiratory Function and Hemodynamics of AIDS Patients with Respiratory Failure.Infection and drug resistance · 2023Article
- Estimating the risk of mortality attributable to recent late HIV diagnosis following admission to the intensive care unit: A single-centre observational cohort study.HIV medicine · 2022Observational
- Article
- Death-related factors in HIV/AIDS patients undergoing hemodialysis in an intensive care unit.Revista do Instituto de Medicina Tropical de Sao Paulo · 2021Article
- In-Hospital Cardiopulmonary Resuscitation of Patients With Human Immunodeficiency Virus Infection: A Population-Based Cohort Study of Epidemiology and Outcomes.Journal of clinical medicine research · 2020Article
- Management of HIV-infected patients in the intensive care unit.Intensive care medicine · 2020Review
- Respiratory virus-associated infections in HIV-infected adults admitted to the intensive care unit for acute respiratory failure: a 6-year bicenter retrospective study (Annals of intensive care · 2020Article
- Outcomes and factors influencing outcomes of critically ill HIV-positive patients in a tertiary care center in South India.Journal of family medicine and primary care · 2019Article
- Cigarette smoke promotes HIV infection of primary bronchial epithelium and additively suppresses CFTR function.Scientific reports · 2018Article
- Outcomes of HIV-associated pneumocystis pneumonia at a South African referral hospital.PloS one · 2018Article
- Epidemiology and Outcomes in Critically Ill Patients with Human Immunodeficiency Virus Infection in the Era of Combination Antiretroviral Therapy.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2017Article
- HIV Infects Bronchial Epithelium and Suppresses Components of the Mucociliary Clearance Apparatus.PloS one · 2017Article
- Six-month survival of critically ill patients with HIV-related disease and tuberculosis: a retrospective study.BMC infectious diseases · 2016Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral studies have described improved outcomes for HIV-infected patients admitted to the intensive care unit (ICU) since the introduction of highly active antiretroviral therapy (HAART). A study was undertaken to examine the outcome from the ICU for HIV-infected patients and to identify prognostic factors.
methodsA retrospective study of HIV-infected adults admitted to a university affiliated hospital ICU between January 1999 and December 2005 was performed. Information was collected on patient demographics, receipt of HAART (no patient began HAART on the ICU), reason for ICU admission and hospital course. Outcomes were survival to ICU discharge and to hospital discharge.
results102 patients had 113 admissions to the ICU; HIV infection was newly diagnosed in 31 patients. Survival (first episode ICU discharge and hospital discharge) was 77% and 68%, respectively, compared with 74% and 65% for general medical patients. ICU and hospital survival was 78% and 67% in those receiving HAART, and 75% and 66% in those who were not. In univariate analysis, factors associated with survival were: haemoglobin (OR = 1.25, 95% CI 1.03 to 1.51, for an increase of 1 g/dl), CD4 count (OR = 1.59, 95% CI 0.98 to 2.58, for a 10-fold increase in cells/microl), APACHE II score (OR = 0.51, 95% CI 0.29 to 0.90, for a 10 unit increase) and mechanical ventilation (OR = 0.29, 95% CI 0.10 to 0.83).
conclusionsThe outcome for HIV-infected patients admitted to the ICU was good and was comparable to that in general medical patients. More than a quarter of patients had newly diagnosed HIV infection. Patients receiving HAART did not have a better outcome.
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