Evidence map›Paper›PMID 17517769›Full record

ArticleNucleic acids research2007

QuickSNP: an automated web server for selection of tagSNPs.

Deepak Grover, Alonzo S Woodfield, Ranjana Verma, Peter P Zandi, Douglas F Levinson, James B Potash

Abstract read
In one paragraph

Article in Nucleic acids research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. A ComprehensiveFrontiers in cellular and infection microbiology · 2018
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  4. Oxidative Stress-Related Genetic Variants May Modify Associations of Phthalate Exposures with Asthma.International journal of environmental research and public health · 2017
    Article
  5. Article
  6. N-Acetyltransferase 2 Genotypes Are Associated With Diisocyanate-Induced Asthma.Journal of occupational and environmental medicine · 2015
    Article
  7. Article
  8. Genetic variants in antioxidant genes are associated with diisocyanate-induced asthma.Toxicological sciences : an official journal of the Society of Toxicology · 2012
    Article
  9. Article
  10. Family-based association of YWHAH in psychotic bipolar disorder.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2009
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Deepak GroverDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.
Alonzo S Woodfield
Ranjana Verma
Peter P Zandi
Douglas F Levinson
James B Potash

Funding

GENETICS OF EARLY ONSET DEPRESSIONR01MH059552 · NIMH · JOHNS HOPKINS UNIVERSITY · PI POTASH, JAMES B. · 1999 to 2008
$2.8M
BIOINFORMATICS TO DISCOVER GENES IN PSYCHIATRIC ILLNESSK01MH072866 · NIMH · JOHNS HOPKINS UNIVERSITY · PI ZANDI, PETER P. · 2005 to 2009
$724k
NIMH NIH HHS K01 MH072866NIMH NIH HHS R01 MH-059552NIMH NIH HHS R01 MH059552
6 · The paper itself

Abstract

Although large-scale genetic association studies involving hundreds to thousands of SNPs have become feasible, the associated cost is substantial. Even with the increased efficiency introduced by the use of tagSNPs, researchers are often seeking ways to maximize resource utilization given a set of SNP-based gene-mapping goals. We have developed a web server named QuickSNP in order to provide cost-effective selection of SNPs, and to fill in some of the gaps in existing SNP selection tools. One useful feature of QuickSNP is the option to select only gene-centric SNPs from a chromosomal region in an automated fashion. Other useful features include automated selection of coding non-synonymous SNPs, SNP filtering based on inter-SNP distances and information regarding the availability of genotyping assays for SNPs and whether they are present on whole genome chips. The program produces user-friendly summary tables and results, and a link to a UCSC Genome Browser track illustrating the position of the selected tagSNPs in relation to genes and other genomic features. We hope the unique combination of features of this server will be useful for researchers aiming to select markers for their genotyping studies. The server is freely available and can be accessed at the URL http://bioinformoodics.jhmi.edu/quickSNP.pl.

Indexed as

InternetPolymorphism, Single NucleotideAlgorithmsAnimalsAutomationChromosome MappingComputational BiologyDatabases, GeneticGenome, HumanGenotypeHumansLinkage DisequilibriumModels, GeneticSequence Analysis, DNASoftwareUser-Computer Interface

Identifiers

PMID17517769
PMCPMC1933212

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.