ArticleInsect biochemistry and molecular biology2007
Specific transcriptional responses to juvenile hormone and ecdysone in Drosophila.
Article in Insect biochemistry and molecular biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 66 citations in OpenAlex.
- Gut hormone signaling drives sex differences in metabolism and behavior.Molecular metabolism · 2026Article
- Transcriptional induction by ecdysone in Drosophila salivary glands involves an increase in chromatin accessibility and acetylation.Nucleic acids research · 2025Article
- Genetic characterization of candidate ecdysteroid kinases in Drosophila melanogaster.G3 (Bethesda, Md.) · 2024Article
- Drosophila postembryonic nervous system development: a model for the endocrine control of development.Genetics · 2023Review
- Endocrine Regulation of Lifespan in Insect Diapause.Frontiers in physiology · 2022Review
- Genome-wide survey of cytochrome P450 genes in the salmon louse Lepeophtheirus salmonis (Krøyer, 1837).Parasites & vectors · 2019Article
- A hormonal cue promotes timely follicle cell migration by modulating transcription profiles.Mechanisms of development · 2017Article
- The dynamic landscape of gene regulation during Bombyx mori oogenesis.BMC genomics · 2017Article
- Article
- Global transcriptional dynamics of diapause induction in non-blood-fed and blood-fed Aedes albopictus.PLoS neglected tropical diseases · 2015Article
- Transcriptome-based identification of ABC transporters in the western tarnished plant bug Lygus hesperus.PloS one · 2014Article
- Microarray Analysis of the Juvenile Hormone Response in Larval Integument of the Silkworm, Bombyx mori.International journal of genomics · 2014Article
- Accessory gland as a site for prothoracicotropic hormone controlled ecdysone synthesis in adult male insects.PloS one · 2013Article
- Review
- Wolbachia as an "infectious" extrinsic factor manipulating host signaling pathways.Frontiers in endocrinology · 2011Article
- Article
- Juvenile hormone regulation of male accessory gland activity in the red flour beetle, Tribolium castaneum.Mechanisms of development · 2009Article
- Molecular analysis of juvenile hormone analog action in controlling the metamorphosis of the red flour beetle, Tribolium castaneum.Archives of insect biochemistry and physiology · 2009Article
- Ecdysone [corrected] receptor isoforms play distinct roles in controlling molting and metamorphosis in the red flour beetle, Tribolium castaneum.Molecular and cellular endocrinology · 2008Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Previous studies have shown that ecdysone (E), and its immediate downstream product 20-hydroxyecdysone (20E), can have different biological functions in insects, suggesting that E acts as a distinct hormone. Here, we use Drosophila larval organ culture in combination with microarray technology to identify genes that are transcriptionally regulated by E, but which show little or no response to 20E. These genes are coordinately expressed for a brief temporal interval at the onset of metamorphosis, suggesting that E acts together with 20E to direct puparium formation. We also show that E74B, pepck, and CG14949 can be induced by juvenile hormone III (JH III) in organ culture, and that CG14949 can be induced by JH independently of protein synthesis. In contrast, E74A and E75A show no response to JH in this system. These studies demonstrate that larval organ culture can be used to identify Drosophila genes that are regulated by hormones other than 20E, and provide a basis for studying crosstalk between multiple hormone signaling pathways.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.