ArticlePlant physiology2007
Expression of genomic AtCYCD2;1 in Arabidopsis induces cell division at smaller cell sizes: implications for the control of plant growth.
Article in Plant physiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 56 citations in OpenAlex.
- GWAS identifies candidate genes controlling adventitious rooting inHorticulture research · 2023Article
- Overexpression of Physcomitrium patens cell cycle regulators leads to larger gametophytes.Scientific reports · 2023Article
- Study on the interaction preference between CYCD subclass and CDK family members at the poplar genome level.Scientific reports · 2022Article
- Ectopic Expression of PoplarFrontiers in plant science · 2022Article
- Genome-Wide Analysis of the Cyclin Gene Family and Their Expression Profile inInternational journal of molecular sciences · 2020Article
- The CDK Inhibitor SIAMESE Targets Both CDKA;1 and CDKB1 Complexes to Establish Endoreplication in Trichomes.Plant physiology · 2020Article
- Phase separation of Arabidopsis EMB1579 controls transcription, mRNA splicing, and development.PLoS biology · 2020Article
- Tomato SD1, encoding a kinase-interacting protein, is a major locus controlling stem development.Journal of experimental botany · 2020Article
- Cyclin-Dependent Kinase Inhibitor GeneInternational journal of molecular sciences · 2020Article
- The RNA helicase, eIF4A-1, is required for ovule development and cell size homeostasis in Arabidopsis.The Plant journal : for cell and molecular biology · 2015Article
- Functional Conservation in the SIAMESE-RELATED Family of Cyclin-Dependent Kinase Inhibitors in Land Plants.The Plant cell · 2015Article
- Endocycles: a recurrent evolutionary innovation for post-mitotic cell growth.Nature reviews. Molecular cell biology · 2014Review
- The Arabidopsis CDK inhibitor ICK3/KRP5 is rate limiting for primary root growth and promotes growth through cell elongation and endoreduplication.Journal of experimental botany · 2013Article
- Genome-wide identification, phylogenetic and co-expression analysis of OsSET gene family in rice.PloS one · 2013Article
- What determines cell size?BMC biology · 2012Article
- Regulation of tomato fruit pericarp development by an interplay between CDKB and CDKA1 cell cycle genes.Journal of experimental botany · 2012Article
- A shift toward smaller cell size via manipulation of cell cycle gene expression acts to smoothen Arabidopsis leaf shape.Plant physiology · 2011Article
- The Arabidopsis D-type cyclin CYCD2;1 and the inhibitor ICK2/KRP2 modulate auxin-induced lateral root formation.The Plant cell · 2011Article
- Expression profiling of cell cycle genes reveals key facilitators of cell production during carpel development, fruit set, and fruit growth in apple (Malusxdomestica Borkh.).Journal of experimental botany · 2011Article
- Walls around tumours - why plants do not develop cancer.Nature reviews. Cancer · 2010Review
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Arabidopsis (Arabidopsis thaliana) CYCD2;1 gene introduced in genomic form increased cell formation in the Arabidopsis root apex and leaf, while generating full-length mRNA, raised CDK/CYCLIN enzyme activity, reduced G1-phase duration, and reduced size of cells at S phase and division. Other cell cycle genes, CDKA;1, CYCLIN B;1, and the cDNA form of CYCD2;1 that produced an aberrantly spliced mRNA, produced smaller or zero increases in CDK/CYCLIN activity and did not increase the number of cells formed. Plants with a homozygous single insert of genomic CYCD2;1 grew with normal morphology and without accelerated growth of root or shoot, not providing evidence that cell formation or CYCLIN D2 controls growth of postembryonic vegetative tissues. At the root apex, cells progressed normally from meristem to elongation, but their smaller size enclosed less growth and a 40% reduction in final size of epidermal and cortical cells was seen. Smaller elongated cell size inhibited endoreduplication, indicating a cell size requirement. Leaf cells were also smaller and more numerous during proliferation and epidermal pavement and palisade cells attained 59% and 69% of controls, whereas laminas reached normal size. Autonomous control of expansion was therefore not evident in abundant cell types that formed tissues of root or leaf. Cell size was reduced by a greater number formed in a tissue prior to cell and tissue expansion. Initiation and termination of expansion did not correlate with cell dimension or number and may be determined by tissue-wide signals acting across cellular boundaries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.