ArticleJournal of bacteriology2007
Two genes encoding protein kinases of the HstK family are involved in synthesis of the minor heterocyst-specific glycolipid in the cyanobacterium Anabaena sp. strain PCC 7120.
Article in Journal of bacteriology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 36 citations in OpenAlex.
- Article
- Lipids productivity of cyanobacterium Anabaena vaginicola in an internally illuminated photobioreactor using LED bar lights.Scientific reports · 2024Article
- Transcriptome and metabolome analyses of response of Synechocystis sp. PCC 6803 to methyl viologen.Applied microbiology and biotechnology · 2021Article
- New insights into the function of the proteins IsiC and IsiD from Synechocystis sp. PCC 6803 under iron limitation.Applied microbiology and biotechnology · 2021Article
- Transcriptome Analysis Reveals IsiA-Regulatory Mechanisms Underlying Iron Depletion and Oxidative-Stress Acclimation inApplied and environmental microbiology · 2020Article
- Article
- Structural and functional insights into the tetrameric photosystem I from heterocyst-forming cyanobacteria.Nature plants · 2019Article
- Tracing the origin and evolution of pseudokinases across the tree of life.Science signaling · 2019Article
- The ABC Transporter Components HgdB and HgdC are Important for Glycolipid Layer Composition and Function of Heterocysts inLife (Basel, Switzerland) · 2018Article
- The composition of the global and feature specific cyanobacterial core-genomes.Frontiers in microbiology · 2015Article
- The regulation of HanA during heterocyst development in cyanobacterium Anabaena sp. PCC 7120.World journal of microbiology & biotechnology · 2014Article
- ppGpp metabolism is involved in heterocyst development in the cyanobacterium Anabaena sp. strain PCC 7120.Journal of bacteriology · 2013Article
- Novel ATP-driven pathway of glycolipid export involving TolC protein.The Journal of biological chemistry · 2011Article
- Identification of ten Anabaena sp. genes that under aerobic conditions are required for growth on dinitrogen but not for growth on fixed nitrogen.Journal of bacteriology · 2011Article
- Cyanobacterial heterocysts.Cold Spring Harbor perspectives in biology · 2010Review
- Compartmentalized function through cell differentiation in filamentous cyanobacteria.Nature reviews. Microbiology · 2010Review
- Mutual regulation of ntcA and hetR during heterocyst differentiation requires two similar PP2C-type protein phosphatases, PrpJ1 and PrpJ2, in Anabaena sp. strain PCC 7120.Journal of bacteriology · 2009Article
- Highly plastic genome of Microcystis aeruginosa PCC 7806, a ubiquitous toxic freshwater cyanobacterium.BMC genomics · 2008Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The filamentous cyanobacterium Anabaena sp. strain PCC 7120 can fix N(2) under oxic conditions, and the activity of nitrogen fixation occurs exclusively in heterocysts, cells differentiated from vegetative cells in response to a limitation of a combined-nitrogen source in the growth medium. At the late stages of heterocyst differentiation, an envelope layer composed of two glycolipids is formed to limit the entry of oxygen so that the oxygen-sensitive nitrogenase can function. The genome of Anabaena sp. strain PCC 7120 possesses a family of 13 genes (the hstK family), all encoding proteins with a putative Ser/Thr kinase domain at their N termini and a His-kinase domain at their C termini. In this study, we showed that the double mutant D4.3 strain, in which two members of this gene family, pkn44 (all1625) and pkn30 (all3691), were both inactivated, failed to fix N(2) in the presence of oxygen (Fox(-)). In an environment without oxygen, a low level of nitrogenase activity was detectable (Fix(+)). Heterocyst development in the mutant D4.3 was delayed by 24 h and arrested at a relatively early stage without the formation of the glycolipid layer (Hgl(-)). Only the minor species of the two heterocyst-specific glycolipids (HGLs) was missing in the mutant. We propose that DevH, a putative transcription factor, coordinates the synthesis of both HGLs, while Pkn44/Pkn30 and the previously characterized PrpJ may represent two distinct regulatory pathways involved in the synthesis of the minor HGL and the major HGL, respectively.
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