Evidence map›Paper›PMID 17512217›Full record

ReviewNeuroImage2007

A review of micro- and macrovascular analyses in the assessment of tumor-associated vasculature as visualized by MR.

Elizabeth Bullitt, David A Reardon, J Keith Smith

Registry-linked trialAbstract readReview
In one paragraph

Review in NeuroImage, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00630292 (Feasibility Study of Vessel Analysis for Noninvasive Diagnosis of Malignancy in Breast Tumors), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00630292 naterminatednot on this mapstarted 2008, after this paper: background citation

Feasibility Study of Vessel Analysis for Noninvasive Diagnosis of Malignancy in Breast Tumors

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2008 to 2009Enrolled6ConditionsBreast CancerArmsMagnetic Resonance Angiography (MRA) of the Breast
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. PD-L1/PD-1 Axis in Glioblastoma Multiforme.International journal of molecular sciences · 2019
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Conventional MRI evaluation of gliomas.The British journal of radiology · 2011
    Review
  9. Article
  10. Article
  11. Article
  12. A review of VEGF/VEGFR-targeted therapeutics for recurrent glioblastoma.Journal of the National Comprehensive Cancer Network : JNCCN · 2011
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. The emerging role of anti-angiogenic therapy for malignant glioma.Current treatment options in oncology · 2008
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Elizabeth BullittCASILab, CB # 7062, University of North Carolina, Chapel Hill, NC 27599, USA. bullitt@med.unc.edu
David A Reardon
J Keith Smith
University of North Carolina at Chapel Hill · US

Funding

3D Cerebral Vessel Location for Surgical PlanningR01EB000219 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULLITT, ELIZABETH · 2002 to 2008
$3.0M
Noninvasive assessment of tumor malignancyR01CA124608 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULLITT, ELIZABETH · 2007 to 2010
$1.8M
NCI NIH HHS R01 CA124608NIBIB NIH HHS R01 EB000219
6 · The paper itself

Abstract

There is currently no noninvasive, reliable method of assessing brain tumor malignancy or of monitoring tumor treatment response. Monitoring changes to tumor vasculature might provide an effective means of assessing both tumor aggressiveness and treatment efficacy. To date, most such research has concentrated upon tumor "microvascular" imaging, with permeability and/or perfusion imaging used to assess vessel changes at the subvoxel level. An alternative approach assesses tumor vasculature at the "macroscopic" level, calculating the numbers and shapes of the larger vessels discriminable by magnetic resonance angiography. This paper provides an overview of magnetic resonance (MR) vascular imaging at both the microscopic (dynamic MR perfusion and permeability) and macroscopic (MR angiographic) levels. The two approaches provide different, complementary information and together could provide important insights into cancer growth as well as new methods of assessing malignancy and tumor treatment response.

Indexed as

Magnetic Resonance AngiographyBlood VesselsBrain NeoplasmsCapillary PermeabilityCerebrovascular CirculationHumansRegional Blood Flow

Identifiers

PMID17512217
PMCPMC2292206
OpenAlexW1995629473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.