ArticleBMC evolutionary biology2007
Evolution of rhodopsin ion pumps in haloarchaea.
Article in BMC evolutionary biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 62 citations in OpenAlex.
- Article
- Cryo-EM structure of the SRI-HtrI complex reveals the cytoplasmic coupling in an archaeal phototaxis system.Nature communications · 2026Article
- Genomic Insights into Bacterioruberin and Halorhodopsin Biosynthetic Genes in 12 Halophilic Archaea Isolated from Korean Solar Salterns.Journal of microbiology and biotechnology · 2026Article
- A Two-Component Regulatory System Mediates Quorum Sensing-Dependent Morphology and Motility Transitions in the ArchaeonbioRxiv : the preprint server for biology · 2025Article
- Strategies of Environmental Adaptation in the Haloarchaeal GeneraMicroorganisms · 2025Article
- Comparative genomics of the highly halophilic Haloferacaceae.Scientific reports · 2024Article
- Article
- Earliest Photic Zone Niches Probed by Ancestral Microbial Rhodopsins.Molecular biology and evolution · 2022Article
- Engineered Bacteriorhodopsin May Induce Lung Cancer Cell Cycle Arrest and Suppress Their Proliferation and Migration.Molecules (Basel, Switzerland) · 2021Article
- Isolation and Taxonomic Characterization of Novel Haloarchaeal Isolates From Indian Solar Saltern: A Brief Review on Distribution of Bacteriorhodopsins and V-Type ATPases in Haloarchaea.Frontiers in microbiology · 2020Article
- Robust Archaeal and Bacterial Communities Inhabit Shallow Subsurface Sediments of the Bonneville Salt Flats.mSphere · 2019Article
- Genotypic and Lipid Analyses of Strains From the Archaeal GenusFrontiers in microbiology · 2018Article
- Article
- Transcriptome analysis of Haloquadratum walsbyi: vanity is but the surface.BMC genomics · 2017Article
- High quality draft genome sequence of an extremely halophilic archaeonStandards in genomic sciences · 2017Article
- A Unique Light-Driven Proton Transportation Signal in Halorhodopsin from Natronomonas pharaonis.Biophysical journal · 2016Article
- Structural and Functional Studies of a Newly Grouped Haloquadratum walsbyi Bacteriorhodopsin Reveal the Acid-resistant Light-driven Proton Pumping Activity.The Journal of biological chemistry · 2015Article
- Horizontal gene transfer, dispersal and haloarchaeal speciation.Life (Basel, Switzerland) · 2015Review
- Microbial ecology of an Antarctic hypersaline lake: genomic assessment of ecophysiology among dominant haloarchaea.The ISME journal · 2014Article
- Evidence from phylogenetic and genome fingerprinting analyses suggests rapidly changing variation in Halorubrum and Haloarcula populations.Frontiers in microbiology · 2014Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe type 1 (microbial) rhodopsins are a diverse group of photochemically reactive proteins that display a broad yet patchy distribution among the three domains of life. Recent work indicates that this pattern is likely the result of lateral gene transfer (LGT) of rhodopsin genes between major lineages, and even across domain boundaries. Within the lineage in which the microbial rhodopsins were initially discovered, the haloarchaea, a similar patchy distribution is observed. In this initial study, we assess the roles of LGT and gene loss in the evolution of haloarchaeal rhodopsin ion pump genes, using phylogenetics and comparative genomics approaches.
resultsMapping presence/absence of rhodopsins onto the phylogeny of the RNA polymerase B' subunit (RpoB') of the haloarchaea supports previous notions that rhodopsins are patchily distributed. The phylogeny for the bacteriorhodopsin (BR) protein revealed two discrepancies in comparison to the RpoB' marker, while the halorhodopsin (HR) tree showed incongruence to both markers. Comparative analyses of bacteriorhodopsin-linked regions of five haloarchaeal genomes supported relationships observed in the BR tree, and also identified two open reading frames (ORFs) that were more frequently linked to the bacteriorhodopsin gene than those genes previously shown to be important to the function and expression of BR.
conclusionThe evidence presented here reveals a complex evolutionary history for the haloarchaeal rhodopsins, with both LGT and gene loss contributing to the patchy distribution of rhodopsins within this group. Similarities between the BR and RpoB' phylogenies provide supportive evidence for the presence of bacteriorhodopsin in the last common ancestor of haloarchaea. Furthermore, two loci that we have designated bacterio-opsin associated chaperone (bac) and bacterio-opsin associated protein (bap) are inferred to have important roles in BR biogenesis based on frequent linkage and co-transfer with bacteriorhodopsin genes.
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