ArticleGenetics2007
A validated whole-genome association study of efficient food conversion in cattle.
Article in Genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
65 citing papers in PubMed, 1 synthesis or guideline pooled it, 192 citations in OpenAlex.
- GWAS and eQTL analysis identifies a SNP associated with both residual feed intake and GFRA2 expression in beef cattle.Scientific reports · 2018Pooled it
- Interaction between cecal microbiota and liver genes of laying ducks with different residual feed intake.Animal microbiome · 2025Article
- Effect of IGF-1 C472T, GH C2141G, and GHR T914A polymorphisms on growth performance and feed efficiency in young Kazakh white-headed cattle.Veterinary world · 2023Article
- Transcriptome Profiling of the Liver in Nellore Cattle Phenotypically Divergent for RFI in Two Genetic Groups.Animals : an open access journal from MDPI · 2023Article
- Association of selected gene polymorphisms with thermotolerance traits in cattle - A review.Animal bioscience · 2022Article
- Comparative Analysis of Multiple GWAS Results Identifies Metabolic Pathways Associated with Resistance toToxins · 2022Article
- Identification of Candidate Genes Regulating Carcass Depth and Hind Leg Circumference in Simmental Beef Cattle Using Illumina Bovine Beadchip and Next-Generation Sequencing Analyses.Animals : an open access journal from MDPI · 2022Article
- Genome-wide investigations reveal the population structure and selection signatures of Nigerian cattle adaptation in the sub-Saharan tropics.BMC genomics · 2022Article
- Review
- Assessing Bos taurus introgression in the UOA Bos indicus assembly.Genetics, selection, evolution : GSE · 2021Article
- The effect of an energy additive on the metabolism of cattle.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2021Article
- An examination of skeletal muscle and hepatic tissue transcriptomes from beef cattle divergent for residual feed intake.Scientific reports · 2021Article
- Whole-Genome Sequence Data Suggest Environmental Adaptation of Ethiopian Sheep Populations.Genome biology and evolution · 2021Article
- A High-Density Genetic Linkage Map and Fine Mapping of QTL For Feed Conversion Efficiency in Common Carp (Frontiers in genetics · 2021Article
- Bovine hepatic miRNAome profiling and differential miRNA expression analyses between beef steers with divergent feed efficiency phenotypes.Scientific reports · 2020Article
- Conditional and unconditional genome-wide association study reveal complicate genetic architecture of human body weight and impacts of smoking.Scientific reports · 2020Article
- Differentially expressed mRNAs, proteins and miRNAs associated to energy metabolism in skeletal muscle of beef cattle identified for low and high residual feed intake.BMC genomics · 2019Article
- Genomic variants identified from whole-genome resequencing of indicine cattle breeds from Pakistan.PloS one · 2019Article
- Identification of muscle-specific candidate genes in Simmental beef cattle using imputed next generation sequencing.PloS one · 2019Article
- Transcriptome analyses reveal reduced hepatic lipid synthesis and accumulation in more feed efficient beef cattle.Scientific reports · 2018Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The genetic factors that contribute to efficient food conversion are largely unknown. Several physiological systems are likely to be important, including basal metabolic rate, the generation of ATP, the regulation of growth and development, and the homeostatic control of body mass. Using whole-genome association, we found that DNA variants in or near proteins contributing to the background use of energy of the cell were 10 times as common as those affecting appetite and body-mass homeostasis. In addition, there was a genic contribution from the extracellular matrix and tissue structure, suggesting a trade-off between efficiency and tissue construction. Nevertheless, the largest group consisted of those involved in gene regulation or control of the phenotype. We found that the distribution of micro-RNA motifs was significantly different for the genetic variants associated with residual feed intake than for the genetic variants in total, although the distribution of promoter sequence motifs was not different. This suggests that certain subsets of micro-RNA are more important for the regulation of this trait. Successful validation depended on the sign of the allelic association in different populations rather than on the strength of the initial association or its size of effect.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.