Evidence map›Paper›PMID 17506641›Full record

ReviewAnnual review of biochemistry2007

Synapses: sites of cell recognition, adhesion, and functional specification.

Soichiro Yamada, W James Nelson

Abstract readReview
In one paragraph

Review in Annual review of biochemistry, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 129 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Structural Basis of GABACurrent topics in behavioral neurosciences · 2022
    Review
  12. Review
  13. Review
  14. Individuality, self and sociality of vascular plants.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Article
  15. Review
  16. The organizing principle of GABABasic & clinical pharmacology & toxicology · 2020
    Review
  17. Review
  18. Perineuronal Nets and Their Role in Synaptic Homeostasis.International journal of molecular sciences · 2019
    Review
  19. Complex formation of APP with GABANature communications · 2019
    Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Soichiro YamadaDepartment of Biomedical Engineering, University of California, Davis, California 95616, USA. syamada@ucdavis.edu
W James Nelson
Stanford University · USUniversity of California, Davis · US

Funding

Topogenesis of NA/K-ATPASE in Polarized Epithelial CellsR37GM035527 · NIGMS · STANFORD UNIVERSITY · PI NELSON, W. JAMES · 2003 to 2012
$7.4M
Topogenesis of Na/K-ATPase in Polarized MDCK Epithelial CellsR01GM035527 · NIGMS · STANFORD UNIVERSITY · PI NELSON, W. JAMES · 1986 to 2015
$3.3M
NIGMS NIH HHS GM35527NIGMS NIH HHS R01 GM035527NIGMS NIH HHS R37 GM035527
6 · The paper itself

Abstract

Synapses are specialized adhesive contacts characteristic of many types of cell-cell interactions involving neurons, immune cells, epithelial cells, and even pathogens and host cells. Cell-cell adhesion is mediated by structurally diverse classes of cell-surface glycoproteins, which form homophilic or heterophilic interactions across the intercellular space. Adhesion proteins bind to a cytoplasmic network of scaffolding proteins, regulators of the actin cytoskeleton, and signal transduction pathways that control the structural and functional organization of synapses. The themes of this review are to compare the organization of synapses in different cell types and to understand how different classes of cell adhesion proteins and cytoplasmic protein networks specify the assembly of functionally distinct synapses in different cell contexts.

Indexed as

Adherens JunctionsAnimalsCadherinsCell AdhesionCell Adhesion MoleculesCell CommunicationEndothelial CellsEpithelial CellsImmune SystemLeukocytesMembrane ProteinsNerve Tissue ProteinsNeural Cell Adhesion MoleculesNeuronsSynapsesTight JunctionsCadherinsCell Adhesion MoleculesMembrane ProteinsNerve Tissue ProteinsNeural Cell Adhesion Molecules

Identifiers

PMID17506641
PMCPMC3368613
OpenAlexW2139501009

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.