Evidence map›Paper›PMID 17506479›Full record

ArticleJournal of clinical laboratory analysis2007

Improved method to calculate the antibody avidity index.

C T Perciani, P S Peixoto, W O Dias, F S Kubrusly, M M Tanizaki

Abstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Trial
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  11. Article
  12. Article
  13. Soluble antigens derived fromCell reports. Medicine · 2021
    Article
  14. Review
  15. Article
  16. Article
  17. Dissociation of systemic and mucosal autoimmunity in cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2020
    Article
  18. A Multi-StageFrontiers in cellular and infection microbiology · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

C T PercianiCentro de Biotecnologia, Instituto Butantan, São Paulo, Brazil.
P S Peixoto
W O Dias
F S Kubrusly
M M Tanizaki

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The methods currently used to determine the immunoglobulin avidity index (AI) require the choice of a reference point in the ELISA titration curve. Since both curves, with and without denaturating reagents, seldom run in parallel, the AI value becomes highly dependent on this reference. The new method for AI calculation presented here takes into account the whole data of the ELISA titration curve in which the final numerical AI is the average of each point.

Indexed as

Antibody AffinityAnimalsAnimals, NewbornEnzyme-Linked Immunosorbent AssayImmunoglobulin GMiceProtein DenaturationReproducibility of ResultsThiosulfatesImmunoglobulin Gpotassium thiosulfateThiosulfates

Identifiers

PMID17506479
PMCPMC6649193

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.