Evidence map›Paper›PMID 17506227›Full record

ReviewDialogues in clinical neuroscience2007

Gender differences in cardiovascular disease and comorbid depression.

Anne Maria Möller-Leimkühler

Open access · diamondAbstract readReview
In one paragraph

Review in Dialogues in clinical neuroscience, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed, 4 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

124 citing papers in PubMed, 4 syntheses or guidelines pooled it, 254 citations in OpenAlex.

  1. Pooled it
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  9. "Bridging the clinical, molecular and genetic perspectives on myocarditis in post-COVID-19 era".International journal of cardiology. Cardiovascular risk and prevention · 2026
    Review
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  19. Plasma and ovarian metabolomic responses to chronic stress in female mice.Metabolomics : Official journal of the Metabolomic Society · 2025
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  20. Trends in hypertensive heart disease-related mortality among older adults in the USA: a retrospective analysis from CDC WONDER between 1999 and 2020.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Article

64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Anne Maria Möller-LeimkühlerDepartment of Psychiatry, Ludwig-Maximilians-University, Munich, Germany. Anne-Maria.Moeller-Leimkuehler@med.uni-muenchen.de
Ludwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although gender is increasingly perceived as a key determinant in health and illness, systematic gender studies in medicine are still lacking. For a long time, cardiovascular disease (CVD) has been seen as a "male" disease, due to men's higher absolute risk compared with women, but the relative risk in women of CVD morbidity and mortality is actually higher. Current knowledge points to important gender differences in age of onset, symptom presentation, management, and outcome, as well as traditional and psychosocial risk factors. Compared with men, CVD risk in women is increased to a greater extent by some traditional factors (e.g., diabetes, hypertension, hypercholesterolemia, obesity), and socioeconomic and psychosocial factors also seem to have a higher impact on CVD in women. With respect to differences in CVD management, a gender bias in favor of men has to be taken into account, in spite of greater age and higher comorbidity in women, possibly contributing to a poorer outcome. Depression has been shown to be an independent risk factor and consequence of CVD; however, concerning gender differences, the results have been inconsistent. Current evidence suggests that depression causes a greater increase in CVD incidence in women, and that female CVD patients experience higher levels of depression than men. Gender aspects should be more intensively considered, both in further research on gender differences in comorbid depression, and in cardiac treatment and rehabilitation, with the goal of making secondary prevention more effective.

Indexed as

Age DistributionCardiovascular DiseasesComorbidityDepressive DisorderDisease SusceptibilityFemaleHumansMalePsychologyQuality of Health CareRisk FactorsSex DistributionSex FactorsSocioeconomic Factors

Identifiers

PMID17506227
PMCPMC3181845
OpenAlexW1724398224

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.