ArticleBrazilian journal of otorhinolaryngology
Optimizing the pharmacological component of integrated balance therapy.
Article in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- True Vertigo Patients in Emergency Department; an Epidemiologic Study.Emergency (Tehran, Iran) · 2016Article
- Effectiveness of a Vestibular Rehabilitation Protocol to Improve the Health-Related Quality of Life and Postural Balance in Patients with Vertigo.International archives of otorhinolaryngology · 2015Article
- Association of cinnarizine and betahistine in prophylactic therapy for Ménière's disease with and without migraine.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2014Review
- A Randomized Trial of Chinese Diaoshi Jifa on Treatment of Dizziness in Meniere's Disease.Evidence-based complementary and alternative medicine : eCAM · 2014Article
- Neuropharmacology of vestibular system disorders.Current neuropharmacology · 2010Article
- Pharmacological modulation of transmitter release by inhibition of pressure-dependent potassium currents in vestibular hair cells.Naunyn-Schmiedeberg's archives of pharmacology · 2009Article
- Review
- Betahistine in the treatment of tinnitus in patients with vestibular disorders.Brazilian journal of otorhinolaryngologyArticle
- Benign Paroxysmal Positional Vertigo: comparison of two recent international guidelines.Brazilian journal of otorhinolaryngologyReview
- Ginkgo Biloba Extract in Ophthalmic and Systemic Disease, With a Focus on Normal-Tension Glaucoma.Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)Review
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Authors and funding
7 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledDrug treatment is an important option for the treatment of peripheral vestibular diseases.
aimTo identify the drug component associated with optimal integrated balance therapy (IBT) for Ménières disease or other peripheral vestibular disorders. MATERIALS AND
methodsAnalysis of a series of patients with Ménières disease patients or patients with other peripheral vestibular disorders that received IBT involving either no medication or betahistine, cinnarizine, clonazepam, flunarizine or Ginkgo biloba during 120 days.
resultsIn Ménières disease, significant differences were observed for all drug therapies (60 days) versus no medication; betahistine was significantly more effective than all other drugs at 60 and 120 days. For non-Ménières disorders, significant differences were observed among betahistine, cinnarizine, clonazepam and flunarizine and no medication after 60 days; all drug therapies were significantly more effective than no medication after 120 days; betahistine, cinnarizine or clonazepam were equally effective and betahistine was more effective than flunarizine and EGb 761. All treatment options were well tolerated.
conclusionsDrug therapies were more effective than no medication in the IBT for patients with Ménières disease or other peripheral vestibular disorders. Betahistine was the most effective medication for patients with Ménières disease and was as effective as cinnarizine and clonazepam for other peripheral vestibular disorders.
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