ReviewNeural plasticity2007
Neurobiology of memory and anxiety: from genes to behavior.
Review in Neural plasticity, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03934385 (Optimizing Exposure Therapy With Mental Rehearsal), which is not on this map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Optimizing Exposure Therapy With Mental Rehearsal
Who cites it
13 citing papers in PubMed.
- The clinical implication of β-arrestins-mediated signaling in memory and cognition.Molecular and cellular biochemistry · 2025Review
- Analysis of theInternational journal of molecular sciences · 2024Article
- Dementia model mice exhibited improvements of neuropsychiatric symptoms as well as cognitive dysfunction with neural cell transplantation.Experimental animals · 2021Article
- Female dominance of both spatial cognitive dysfunction and neuropsychiatric symptoms in a mouse model of Alzheimer's disease.Experimental animals · 2021Article
- Delayed injury of hippocampal interneurons after neonatal hypoxia-ischemia and therapeutic hypothermia in a murine model.Hippocampus · 2018Article
- Intermittent fasting uncovers and rescues cognitive phenotypes in PTEN neuronal haploinsufficient mice.Scientific reports · 2018Article
- γ-aminobutyric acid transporter-1 is involved in anxiety-like behaviors and cognitive function in knockout mice.Experimental and therapeutic medicine · 2015Article
- Effects of a Flavonoid-Rich Fraction on the Acquisition and Extinction of Fear Memory: Pharmacological and Molecular Approaches.Frontiers in behavioral neuroscience · 2015Article
- Sequential Astrocytic 5-HT2B Receptor Stimulation, [Ca(2+)]i Regulation, Glycogenolysis, Glutamate Synthesis, and K(+) Homeostasis are Similar but Not Identical in Learning and Mood Regulation.Frontiers in integrative neuroscience · 2015Article
- Adenosine A(2A) receptors in psychopharmacology: modulators of behavior, mood and cognition.Current neuropharmacology · 2009Article
- Increased cognitive functioning in symptomatic Huntington's disease as revealed by behavioral and event-related potential indices of auditory sensory memory and attention.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2008Article
- Enhancement of anxiety, facilitation of avoidance behavior, and occurrence of adult-onset obesity in mice lacking mitochondrial cyclophilin D.Neuroscience · 2008Article
- The importance of cognitive phenotypes in experimental modeling of animal anxiety and depression.Neural plasticity · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Interaction of anxiety and memory represents an essential feature of CNS functioning. This paper reviews experimental data coming from neurogenetics, neurochemistry, and behavioral pharmacology (as well as parallel clinical findings) reflecting different mechanisms of memory-anxiety interplay, including brain neurochemistry, circuitry, pharmacology, neuroplasticity, genes, and gene-environment interactions. It emphasizes the complexity and nonlinearity of such interplay, illustrated by a survey of anxiety and learning/memory phenotypes in various genetically modified mouse models that exhibit either synergistic or reciprocal effects of the mutation on anxiety levels and memory performance. The paper also assesses the putative role of different neurotransmitter systems and neuropeptides in the regulation of memory processes and anxiety, and discusses the role of neural plasticity in these mechanisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.