ArticleAntimicrobial agents and chemotherapy2007
Atorvastatin is 10-fold more active in vitro than other statins against Plasmodium falciparum.
Article in Antimicrobial agents and chemotherapy, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 47 citations in OpenAlex.
- Treatment Reducing Endothelial Activation Protects against Experimental Cerebral Malaria.Pathogens (Basel, Switzerland) · 2022Article
- Primaquine derivatives: Modifications of the terminal amino group.European journal of medicinal chemistry · 2019Review
- Prenylquinones in Human Parasitic Protozoa: Biosynthesis, Physiological Functions, and Potential as Chemotherapeutic Targets.Molecules (Basel, Switzerland) · 2019Review
- Synthesis and biological evaluation of 1-alkylaminomethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii.Bioorganic & medicinal chemistry · 2019Article
- Atorvastatin: In-Vivo Synergy with Metronidazole as Anti-The Korean journal of parasitology · 2018Article
- Article
- Activity of Fluorine-Containing Analogues of WC-9 and Structurally Related Analogues against Two Intracellular Parasites: Trypanosoma cruzi and Toxoplasma gondii.ChemMedChem · 2016Article
- Antileishmanial effect of mevastatin is due to interference with sterol metabolism.Parasitology research · 2015Article
- Aryloxyethyl Thiocyanates Are Potent Growth Inhibitors of Trypanosoma cruzi and Toxoplasma gondii.ChemMedChem · 2015Article
- In vitro interaction of lumefantrine and piperaquine by atorvastatin against Plasmodium falciparum.Malaria journal · 2014Article
- Chemical and genetic validation of the statin drug target to treat the helminth disease, schistosomiasis.PloS one · 2014Article
- Short-term pretreatment with atorvastatin attenuates left ventricular dysfunction, reduces infarct size and apoptosis in acute myocardial infarction rats.International journal of clinical and experimental medicine · 2014Article
- Design, synthesis and biological evaluation of WC-9 analogs as antiparasitic agents.European journal of medicinal chemistry · 2013Article
- Improvement of the efficacy of dihydroartemisinin with atorvastatin in an experimental cerebral malaria murine model.Malaria journal · 2013Article
- Impact of methylene blue and atorvastatin combination therapy on the apparition of cerebral malaria in a murine model.Malaria journal · 2013Article
- Drug repurposing screen reveals FDA-approved inhibitors of human HMG-CoA reductase and isoprenoid synthesis that block Cryptosporidium parvum growth.Antimicrobial agents and chemotherapy · 2013Article
- In vitro antimalarial activity and drug interactions of fenofibric acid.Antimicrobial agents and chemotherapy · 2012Article
- Proveblue (methylene blue) as an antimalarial agent: in vitro synergy with dihydroartemisinin and atorvastatin.Antimicrobial agents and chemotherapy · 2012Article
- Atorvastatin treatment is effective when used in combination with mefloquine in an experimental cerebral malaria murine model.Malaria journal · 2012Article
- Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage.Malaria journal · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.