ArticleThe journal of pain2007
Substance use disorders in a primary care sample receiving daily opioid therapy.
Article in The journal of pain, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
89 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Adverse events associated with medium- and long-term use of opioids for chronic non-cancer pain: an overview of Cochrane Reviews.The Cochrane database of systematic reviews · 2017Pooled it
- 2017 HIVMA of IDSA Clinical Practice Guideline for the Management of Chronic Pain in Patients Living With HIV.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017Guideline
- Guideline
- Pooled it
- Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain.The journal of pain · 2009Guideline
- Improving Adherence to Long-term Opioid Therapy Guidelines to Reduce Opioid Misuse in Primary Care: A Cluster-Randomized Clinical Trial.JAMA internal medicine · 2017Trial
- The Contribution of Differential Opioid Responsiveness to Identification of Opioid Risk in Chronic Pain Patients.The journal of pain · 2015Trial
- Trial
- Association between substance use disorder status and pain-related function following 12 months of treatment in primary care patients with musculoskeletal pain.The journal of pain · 2011Trial
- Predictors of long-term opioid use among patients with painful lumbar spine conditions.The journal of pain · 2010Trial
- Brief alcohol intervention in the emergency department: moderators of effectiveness.Journal of studies on alcohol and drugs · 2008Trial
- International perspective on healthcare provider gender bias in musculoskeletal pain management: a scoping review.BMJ open · 2026Article
- Prescription Opioid Use Disorder Among Adults Reporting Prescription Opioid Use With or Without Misuse in the United States.The Journal of clinical psychiatry · 2024Article
- An acceptance and commitment therapy-based intervention for opioid use disorder risk in individuals with cancer: A treatment development study.Journal of contextual behavioral science · 2023Article
- Opioid Use Among Medicare Beneficiaries With Knee Osteoarthritis: Prevalence and Correlates of Chronic Use.Arthritis care & research · 2023Article
- Factors associated with strong opioid use for noncancer pain in patients with chronic intestinal failure.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2023Article
- Sociocultural factors associated with persistent prescription opioid use (PPOU) among Puerto Rican adults in Massachusetts.PloS one · 2023Article
- Exploratory evaluation of spinal cord stimulation with dynamic pulse patterns: a promising approach to improve stimulation sensation, coverage of pain areas, and expected pain relief.Frontiers in pain research (Lausanne, Switzerland) · 2023Article
- Societal Cost of Opioid Use in Symptomatic Knee Osteoarthritis Patients in the United States.Arthritis care & research · 2022Article
- International perspective on healthcare provider gender bias in musculoskeletal pain management: a scoping review protocol.BMJ open · 2022Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
unlabelledThe primary goal of this paper was to present a comprehensive picture of substance use disorders in a sample of patients receiving opioid therapy from their primary care physician. A second goal was to determine the relation of positive urine screens and aberrant drug behaviors to opioid use disorders. The study recruited 801 adults receiving daily opioid therapy from the primary care practices of 235 family physicians and internists in 6 health care systems in Wisconsin. The 6 most common pain diagnoses were degenerative arthritis, low back pain, migraine headaches, neuropathy, and fibromyalgia. The point prevalence of current (DSM-IV criteria in the past 30 days) substance abuse and/or dependence was 9.7% (n=78) and 3.8% (30) for an opioid use disorder. A logistic regression model found that current substance use disorders were associated with age between 18 and 30 (OR=6.17: 1.99 to 19.12), severity of lifetime psychiatric disorders (OR=6.17; 1.99 to 19.12), a positive toxicology test for cocaine (OR=5.92; 2.60 to 13.50) or marijuana (OR=3.52; 1.85 to 6.73), and 4 aberrant drug behaviors (OR=11.48; 6.13 to 21.48). The final model for opioid use disorders was limited to aberrant behaviors (OR=48.27; 13.63 to 171.04) as the other variables dropped out of the model. PERSPECTIVE: This study found that the frequency of opioid use disorders was 4 times higher in patients receiving opioid therapy compared with general population samples (3.8% vs 0.9%). The study also provides quantitative data linking aberrant drug behaviors to opioid use disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.