Evidence map›Paper›PMID 17499385›Full record

ReviewAdvanced drug delivery reviews2007

Matrices and scaffolds for drug delivery in dental, oral and craniofacial tissue engineering.

Eduardo K Moioli, Paul A Clark, Xuejun Xin, Shan Lal, Jeremy J Mao

Abstract readReview
In one paragraph

Review in Advanced drug delivery reviews, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 167 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Biocompatible and Biomaterials Application in Drug Delivery System in Oral Cavity.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
  9. Local Drug Delivery Systems for Vital Pulp Therapy: A New Hope.International journal of biomaterials · 2021
    Review
  10. Review
  11. Tooth Formation: Are the Hardest Tissues of Human Body Hard to Regenerate?International journal of molecular sciences · 2020
    Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Nanomaterials for Tissue Engineering In Dentistry.Nanomaterials (Basel, Switzerland) · 2016
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Eduardo K MoioliColumbia University, Tissue Engineering and Regenerative Medicine Laboratory (TERML), College of Dental Medicine, Fu Foundation School of Engineering and Applied Sciences, Department of Biomedical Engineering, New York, NY 10032, USA.
Paul A Clark
Xuejun Xin
Shan Lal
Jeremy J Mao
Columbia University · USUW Health University Hospital · US

Funding

Regeneration of Clinically Relevant Orofacial Tissues in Pre-Clinical ModelsRC2DE020767 · NIDCR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAO, JEREMY J · 2009 to 2010
$2.0M
Stem Cell-Driven Regeneration of the Mandibular JointR01DE015391 · NIDCR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MAO, JEREMY J. · 2003 to 2006
$1.6M
ENGINEERING CRANIOFACIAL OSTEOGENESIS--MECHANICAL FORCESR01DE013964 · NIDCR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MAO, JEREMY J. · 2000 to 2004
$1.3M
Functional Tissue Engineering of Articular CondyleR01EB002332 · NIBIB · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MAO, JEREMY J. · 2003 to 2006
$1.3M
NIBIB NIH HHS EB02332NIBIB NIH HHS R01 EB002332NIDCR NIH HHS DE13964NIDCR NIH HHS DE15391NIDCR NIH HHS R01 DE013964NIDCR NIH HHS R01 DE015391NIDCR NIH HHS RC2 DE020767
6 · The paper itself

Abstract

Current treatments for diseases and trauma of dental, oral and craniofacial (DOC) structures rely on durable materials such as amalgam and synthetic materials, or autologous tissue grafts. A paradigm shift has taken place to utilize tissue engineering and drug delivery approaches towards the regeneration of these structures. Several prototypes of DOC structures have been regenerated such as temporomandibular joint (TMJ) condyle, cranial sutures, tooth structures and periodontium components. However, many challenges remain when taking in consideration the high demand for esthetics of DOC structures, the complex environment and yet minimal scar formation in the oral cavity, and the need for accommodating multiple tissue phenotypes. This review highlights recent advances in the regeneration of DOC structures, including the tooth, periodontium, TMJ, cranial sutures and implant dentistry, with specific emphasis on controlled release of signaling cues for stem cells, biomaterial matrices and scaffolds, and integrated tissue engineering approaches.

Indexed as

Biocompatible MaterialsCraniofacial AbnormalitiesDental ImplantationDrug Delivery SystemsHumansIntercellular Signaling Peptides and ProteinsPeriodontal DiseasesRegenerationTemporomandibular JointTissue EngineeringTooth DiseasesBiocompatible MaterialsIntercellular Signaling Peptides and Proteins

Identifiers

PMID17499385
PMCPMC4035021
OpenAlexW2059289539

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.