ArticleGenomics2007
In search of polymorphic Alu insertions with restricted geographic distributions.
Article in Genomics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 36 citations in OpenAlex.
- AnNAR genomics and bioinformatics · 2022Article
- Evaluation of the InnoTyper21® system for the applications into trace and degraded DNA in the Korean population.International journal of legal medicine · 2020Article
- Mitochondrial Genome and Nuclear Markers Provide New Insight into the Evolutionary History of Macaques.PloS one · 2016Article
- Detecting Alu insertions from high-throughput sequencing data.Nucleic acids research · 2013Article
- Mobile element scanning (ME-Scan) identifies thousands of novel Alu insertions in diverse human populations.Genome research · 2013Article
- An Alu-based phylogeny of gibbons (hylobatidae).Molecular biology and evolution · 2012Article
- Reading TE leaves: new approaches to the identification of transposable element insertions.Genome research · 2011Article
- Alu repeat discovery and characterization within human genomes.Genome research · 2011Article
- BTECH: a platform to integrate genomic, transcriptomic and epigenomic alterations in brain tumors.Neuroinformatics · 2011Article
- Restless genomes humans as a model organism for understanding host-retrotransposable element dynamics.Advances in genetics · 2011Review
- Mobile element scanning (ME-Scan) by targeted high-throughput sequencing.BMC genomics · 2010Article
- Modeling neutral evolution of Alu elements using a branching process.BMC genomics · 2010Article
- The impact of retrotransposons on human genome evolution.Nature reviews. Genetics · 2009Review
- Gene flow and genetic structure in the Galician population (NW Spain) according to Alu insertions.BMC genetics · 2008Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Alu elements are transposable elements that have reached over one million copies in the human genome. Some Alu elements inserted in the genome so recently that they are still polymorphic for insertion presence or absence in human populations. Recently, there has been an increasing interest in using Alu variation for studies of human population genetic structure and inference of individual geographic origin. Currently, this requires a high number of Alu loci. Here, we used a linker-mediated polymerase chain reaction method to preferentially identify low-frequency Alu elements in various human DNA samples with different geographic origins. The candidate Alu loci were subsequently genotyped in 18 worldwide human populations (approximately 370 individuals), resulting in the identification of two new Alu insertions restricted to populations of African ancestry. Our results suggest that it may ultimately become possible to correctly infer the geographic affiliation of unknown samples with high levels of confidence without having to genotype as many as 100 Alu loci. This is desirable if Alu insertion polymorphisms are to be used for human evolution studies or forensic applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.