Evidence map›Paper›PMID 17496348›Full record

ReviewImmunologic research2007

Transcription factors in the control of dendritic cell life cycle.

Arpita S Bharadwaj, Devendra K Agrawal

Abstract readReview
PubMed Publisher
In one paragraph

Review in Immunologic research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Case Report: A novelFrontiers in immunology · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Arpita S BharadwajDepartment of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, NE 68178, USA.
Devendra K Agrawal
Creighton University · US

Funding

APOPTOSIS OF SMOOTH MUSCLE CELLS IN CAROTID PLAQUESR01HL073349 · NHLBI · CREIGHTON UNIVERSITY · PI AGRAWAL, DEVENDRA K. · 2004 to 2013
$2.6M
FLT3-LIGAND, IMMUNOMODULATION AND THERAPY IN ASTHMAR01HL070885 · NHLBI · CREIGHTON UNIVERSITY · PI AGRAWAL, DEVENDRA K. · 2004 to 2008
$1.1M
NHLBI NIH HHS R01 HL 070885NHLBI NIH HHS R01 HL 073349
6 · The paper itself

Abstract

Dendritic cells (DCs) are potent antigen-presenting cells that guard all parts of the body. They have the unique ability to prime T cells and generate primary immune responses. Their journey beginning with the development from precursor cells and ending with their death is controlled by a group of transcription factors. Some of the transcription factors like PU.1 are involved in more than one stage of DC life. Other transcription factors including Ikaros and JAK3 are involved in the development of more than one cell type. For a long time, the cellular and molecular mechanisms underlying the development, differentiation, maturation, and other stages of DC life were not well understood. However, in recent years novel information has been published by many researchers to better understand the molecular mechanisms of the development and function of DCs in immunological diseases such as asthma, cancer, autoimmunity, and transplantation. This review will discuss the various transcription factors and signaling pathways involved in each stage of the life cycle of DCs.

Indexed as

Cell DifferentiationSignal TransductionAnimalsAntigen PresentationDendritic CellsHumansIkaros Transcription FactorMiceProto-Oncogene ProteinsProto-Oncogene Protein Spi-1Trans-ActivatorsTranscription FactorsIkaros Transcription FactorProto-Oncogene ProteinsProto-Oncogene Protein Spi-1Trans-ActivatorsTranscription Factors

Identifiers

PMID17496348
OpenAlexW2037512187

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.