Trial reportAJNR. American journal of neuroradiology2007
Apollo stent for symptomatic atherosclerotic intracranial stenosis: study results.
Trial report in AJNR. American journal of neuroradiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- Drug-eluting stent versus bare metal stent for symptomatic intracranial stenosis: a comparative systematic review and meta-analysis study.European journal of clinical pharmacology · 2025Pooled it
- Percutaneous transluminal angioplasty and/or stenting for the treatment of basilar artery stenosis: a systematic review and meta-analysis.Neuroradiology · 2023Pooled it
- Comparison of Drug-Eluting Stent With Bare-Metal Stent in Patients With Symptomatic High-grade Intracranial Atherosclerotic Stenosis: A Randomized Clinical Trial.JAMA neurology · 2022Trial
- Multicenter Prospective Trial of Stent Placement in Patients with Symptomatic High-Grade Intracranial Stenosis.AJNR. American journal of neuroradiology · 2016Trial
- Stent angioplasty of intracranial stenosis: single center experience of 54 cases.Clinical neuroradiology · 2012Trial
- Application of balloon-expandable stent angioplasty with dIstal support of the stent-retriever (BASIS-Stent) technique for acute intracranial artery atherosclerosis-related occlusion.Journal of neurointerventional surgery · 2026Article
- Endovascular Therapy for Intracranial Atherosclerotic Stenosis: Evidence and Controversies.Journal of neuroendovascular therapy · 2026Review
- Article
- Recanalization of atherosclerotic stenosis and occlusion of intracranial vertebrobasilar artery.IBRO neuroscience reports · 2025Review
- Article
- Current status and outlook of biodegradable metals in neuroscience and their potential applications as cerebral vascular stent materials.Bioactive materials · 2022Review
- Effect of a Drug-Eluting Stent vs. Bare Metal Stent for the Treatment of Symptomatic Intracranial and Vertebral Artery Stenosis.Frontiers in neurology · 2022Article
- Balloon-mounted stenting for ICAS in a multicenter registry study in China: a comparison with the WEAVE/WOVEN trial.Journal of neurointerventional surgery · 2021Article
- Application of High-Resolution Flat Detector Computed Tomography in Stent Implantation for Intracranial Atherosclerotic Stenosis.Frontiers in neuroscience · 2021Article
- Cerebrovascular Drug-Eluting Stent versus Bare-Metal Stent in the Treatment of Vertebral Artery Stenosis: A Non-Inferiority Randomized Clinical Trial.Journal of stroke · 2019Article
- Enterprise stent for symptomatic complex intracranial atherosclerotic stenosis: safety and efficiency.Journal of interventional medicine · 2018Article
- Stenting for symptomatic intracranial arterial stenosis in China: 1-year outcome of a multicentre registry study.Stroke and vascular neurology · 2018Article
- The learning curve associated with intracranial angioplasty and stenting: analysis from a single center.Annals of translational medicine · 2018Article
- Intracranial artery stenosis: Current status of evaluation and treatment in China.Chronic diseases and translational medicine · 2017Article
- Outcomes of tailored angioplasty and/or stenting for symptomatic intracranial atherosclerosis: a prospective cohort study after SAMMPRIS.Journal of neurointerventional surgery · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeA recent trial shows an 8.3 per 100-patient-years' ischemic stroke rate in the territory of the intracranial stenotic artery, despite aspirin treatment. Our aim was to prospectively study the feasibility and outcome of a new intracranial balloon-expandable Apollo stent for symptomatic atherosclerotic intracranial stenosis (SAIS). MATERIALS AND
methodsForty-six patients (41 men and 5 women; median, 54 years of age) with forty-eight >or=50% SAISs were enrolled. Procedural feasibility was evaluated by stent success (residual stenosis <or=30%) and procedural time. The primary end point was ischemic stroke in the target-lesion artery territory, including any stroke and death within 30 days.
resultsForty-four lesions (91.7%) obtained stent success within a median procedural time of 50.6 minutes. Severe tortuosity correlated with stent failure. Three patients (6.5%, 3/46) had minor strokes within 30 days. All patients were available for follow-up (46 had 30-day follow-up, 45 had 6-month follow-up, 44 had 12- and 18-month follow-up, and 24 had follow-up of >or=24 months), which varied from 1 month to 30.7 months (median, 23.9 months). After 30 days, 1 patient (2.2%, 1/46) developed minor stroke in the target-lesion artery territory at 6.7 months. Primary end point rate was 4.3 per 100 patient years. Angiographic follow-up was performed in 25 patients. Seven restenoses (28%, 7/25) were detected, 1 of which was symptomatic.
conclusionAngioplasty with the Apollo stent for symptomatic atherosclerotic intracranial stenosis is feasible. Severe tortuosity is an independent predictor of stent failure. Our clinical outcome seems to compare favorably with results of aspirin therapy, but the restenotic rate was high.
Indexed as
Identifiers
17494651PMC8134340W2115500560What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.