Trial reportIntensive care medicine2007
Assist-control ventilation vs. low levels of pressure support ventilation on sleep quality in intubated ICU patients.
Trial report in Intensive care medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01573481 (Pressure Controlled Ventilation Versus Pressure Support Ventilation During the Night), which is not on this map. Cited by 37 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pressure Controlled Ventilation Versus Pressure Support Ventilation During the Night: New Strategy of Mechanical Ventilation Weaning?
Who cites it
37 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Nocturnal Pressure Controlled Ventilation Improves Sleep Efficiency in Patients Receiving Mechanical Ventilation.Respiratory care · 2024Pooled it
- A Systematic Review of Sleep Measurement in Critically Ill Patients.Frontiers in neurology · 2020Pooled it
- Non-pharmacological interventions for sleep promotion in the intensive care unit.The Cochrane database of systematic reviews · 2015Pooled it
- A meta-analysis of sleep-promoting interventions during critical illness.The American journal of medicine · 2015Pooled it
- Patient-ventilator synchrony and sleep quality with proportional assist and pressure support ventilation.Intensive care medicine · 2013Trial
- Sleep physiology and critical illness: A narrative review.Journal of the Intensive Care Society · 2026Review
- Optimizing Sleep Disorder Management in Hospitalized Patients: Practical Approach for Healthcare Providers.Brain and behavior · 2025Review
- Reply to Letter to Editor Concerning "Nocturnal Pressure Controlled Ventilation Improves Sleep Efficiency in Patients Receiving Mechanical Ventilation".Respiratory care · 2024Article
- Nocturnal Pressure Support Ventilation: Truth or Dare?Respiratory care · 2024Article
- Impact of sleep disturbances on outcomes in intensive care units.Critical care (London, England) · 2024Observational
- Sleep during and following critical illness: A narrative review.World journal of critical care medicine · 2023Review
- Causes, Consequences, and Treatments of Sleep and Circadian Disruption in the ICU: An Official American Thoracic Society Research Statement.American journal of respiratory and critical care medicine · 2023Article
- Sleep and critical illness: a review.Frontiers in medicine · 2023Review
- Adding Insult to Injury: Sleep Deficiency in Hospitalized Patients.Clinics in chest medicine · 2022Review
- Updated Perspectives on the Management of Sleep Disorders in the Intensive Care Unit.Nature and science of sleep · 2021Review
- Pharmacological and non-pharmacological interventions to promote sleep in intensive care units: a critical review.Sleep & breathing = Schlaf & Atmung · 2020Review
- Sleep and Delirium in Older Adults.Current sleep medicine reports · 2020Review
- Sleep in the Intensive Care Unit: Strategies for Improvement.Seminars in respiratory and critical care medicine · 2019Review
- The effects of mechanical ventilation on the quality of sleep of hospitalised patients in the Intensive Care Unit.Romanian journal of anaesthesia and intensive care · 2018Review
- Sleep quality and circadian rhythm disruption in the intensive care unit: a review.Nature and science of sleep · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare the impact of assist-control ventilation (ACV) and pressure support ventilation with 6 cmH2O inspiratory pressure (low PSV) on sleep quality.
designProspective randomized cross-over study. PATIENTS: Twenty intubated and mechanically ventilated patients for acute on chronic respiratory failure. MEASUREMENTS: Patients were monitored by standard polysomnography at the end of their weaning period. Patients were assigned to receive either ACV from 10 p.m. to 2 a.m. and low PSV from 2 a.m. to 6 a.m. (ACV/low PSV group) or low PSV from 10 p.m. to 2 a.m. and ACV from 2 a.m. to 6 a.m. (low PSV/ACV group).
resultsThere were significant increases in stages 1 and 2 non-rapid eye movement (NREM) sleep and reduction in wakefulness during the first part of the night and significant increases in stages 3 and 4 NREM sleep during the second part of the night were observed with ACV compared to low PSV. A significant negative correlation was observed between the perceived sleep quality and the amount of wakefulness while the amount of stage 2 NREM sleep was positively correlated with perceived sleep quality.
conclusionsACV was significantly associated with a better sleep quality than those recorded during pressure support. The perception of sleep quality appeared to be better with ACV than with low PSV. On the basis of these results we recommend that intubated and mechanically ventilated patients for acute on chronic respiratory failure should be reventilated at night during their weaning period.
Indexed as
Identifiers
17492431What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.