ArticleImmunity & ageing : I & A2007
NK cell compartment in patients with coronary heart disease.
Article in Immunity & ageing : I & A, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 45 citations in OpenAlex.
- Natural killer (NK) cell deficit in coronary artery disease: no aberrations in phenotype but sustained reduction of NK cells is associated with low-grade inflammation.Clinical and experimental immunology · 2014Trial
- Immunophenotypic Assessment of Natural Killer Cell Degranulation and Monocyte Function from Cryopreserved Peripheral Blood Mononuclear Cells.Methods in molecular biology (Clifton, N.J.) · 2027Article
- Harnessing the NKG2D immune surveillance pathway using engineered T-cells for the treatment of human disease.Human vaccines & immunotherapeutics · 2026Review
- Article
- Single-Cell Analysis Reveals Novel Immune Perturbations in Fibrotic Hypersensitivity Pneumonitis.American journal of respiratory and critical care medicine · 2024Article
- Decreased natural killer cell activity as a potential predictor of hypertensive incidence.Frontiers in immunology · 2024Article
- Transcriptional profiles associated with coronary artery disease in type 2 diabetes mellitus.Frontiers in endocrinology · 2024Article
- Tissue-Dependent Adaptations and Functions of Innate Lymphoid Cells.Frontiers in immunology · 2022Review
- Heartbreakers or Healers? Innate Lymphoid Cells in Cardiovascular Disease and Obesity.Frontiers in immunology · 2022Review
- Dysregulated Immunity in Pulmonary Hypertension: From Companion to Composer.Frontiers in physiology · 2022Review
- Perforin, COVID-19 and a possible pathogenic auto-inflammatory feedback loop.Scandinavian journal of immunology · 2021Review
- Unbiased Screening Identifies Functional Differences in NK Cells After Early Life Psychosocial Stress.Frontiers in immunology · 2021Article
- The Role of Natural Killer (NK) Cells in Acute Coronary Syndrome: A Comprehensive Review.Biomolecules · 2020Review
- Lymphocytic subsets play distinct roles in heart diseases.Theranostics · 2019Review
- The interstitium in cardiac repair: role of the immune-stromal cell interplay.Nature reviews. Cardiology · 2018Review
- Effect of Aging on NK Cell Population and Their Proliferation at Ex Vivo Culture Condition.Analytical cellular pathology (Amsterdam) · 2018Article
- Natural killer cells in inflammatory heart disease.Clinical immunology (Orlando, Fla.) · 2017Review
- High-resolution phenotyping identifies NK cell subsets that distinguish healthy children from adults.PloS one · 2017Article
- Differential loss of natural killer cell activity in patients with acute myocardial infarction and stable angina pectoris.International journal of clinical and experimental pathology · 2015Article
- Interplay of NK cells and monocytes in vascular inflammation and myocardial infarction.Frontiers in physiology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundViral and bacterial infections have been considered as a risk factor for Coronary Heart Disease (CHD). NK cells, as a first line of defense against those infections, may play a role in CHD development. Thus, the main aim of our study was to determine NK cell compartment in patients with CHD undergoing coronary artery by-pass grafting.
resultsNinety three patients with CHD were included into the study; the control group consisted of 49 healthy volunteers. As compared to controls, CHD patients had lower NK cytotoxic activity. CHD group had also a decreased absolute number and percentage of total NK cells and CD3-CD56dim cytotoxic NK subset. In addition, we observed tendency toward lower percentage of the CD3-CD56bright regulatory NK subset and CD3-CD56+IFN-gamma+ cells in CHD patients.
conclusionThese data indicate that CHD is associated with an impairment of NK cells compartment.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.