Evidence map›Paper›PMID 17488473›Full record

ReviewJournal of cellular and molecular medicine

Gene transfer strategies in tissue engineering.

Oliver Bleiziffer, Elof Eriksson, Feng Yao, Raymund E Horch, Ulrich Kneser

Abstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Review
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  5. Article
  6. Review
  7. Fine-Tunable and Injectable 3D Hydrogel for On-Demand Stem Cell Niche.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019
    Article
  8. Article
  9. Article
  10. Innovations in gene and growth factor delivery systems for diabetic wound healing.Journal of tissue engineering and regenerative medicine · 2018
    Review
  11. Article
  12. Article
  13. Article
  14. Tissue engineering and regenerative medicine -where do we stand?Journal of cellular and molecular medicine · 2012
    Review
  15. Article
  16. Article
  17. Review
  18. Scars and perforator-based flaps in the abdominal region: a contraindication?Canadian journal of surgery. Journal canadien de chirurgie · 2010
    Article
  19. [The development of plastic surgery: retrospective view of 80 years of "Der Chirurg" (The Surgeon)].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2009
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Oliver BleizifferDepartment of Plastic and Hand Surgery, University of Erlangen Medical Center, Krankenhausstrasse 12, 91054 Erlangen, Germany.
Elof Eriksson
Feng Yao
Raymund E Horch
Ulrich Kneser

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aiming for regeneration of severed or lost parts of the body, the combined application of gene therapy and tissue engineering has received much attention by regenerative medicine. Techniques of molecular biology can enhance the regenerative potential of a biomaterial by co-delivery of therapeutic genes, and several different strategies have been used to achieve that goal. Possibilities for application are many-fold and have been investigated to regenerate tissues such as skin, cartilage, bone, nerve, liver, pancreas and blood vessels. This review discusses advantages and problems encountered with the different gene delivery strategies as far as they relate to tissue engineering, analyses the positive aspects of polymeric gene delivery from matrices and discusses advances and future challenges of gene transfer strategies in selected tissues.

Indexed as

Gene Transfer TechniquesAnimalsForecastingGenetic TherapyGenetic VectorsHumansRegenerative MedicineTissue Engineering

Identifiers

PMID17488473
PMCPMC3822823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.