ReviewThe Biochemical journal2007
Stem cells in the adult pancreas and liver.
Review in The Biochemical journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 38 citations in OpenAlex.
- HCV and tumor-initiating stem-like cells.Frontiers in physiology · 2022Review
- Pancreatic DCLK1Cancer letters · 2018Article
- Oncogenic signaling pathways and origins of tumor-initiating stem-like cells of hepatocellular carcinomas induced by hepatitis C virus, alcohol and/or obesity.Hepatology international · 2014Article
- Tumor-initiating stem-like cells and drug resistance: carcinogenesis through Toll-like receptors, environmental factors, and virus.Drug delivery and translational research · 2013Article
- Cancer stem cells and therapeutic targets: an emerging field for cancer treatment.Drug delivery and translational research · 2013Article
- Isolation of muscle-derived stem/progenitor cells based on adhesion characteristics to collagen-coated surfaces.Methods in molecular biology (Clifton, N.J.) · 2013Article
- Cancer stem cells generated by alcohol, diabetes, and hepatitis C virus.Journal of gastroenterology and hepatology · 2012Review
- Alcohol and hepatitis C virus--interactions in immune dysfunctions and liver damage.Alcoholism, clinical and experimental research · 2010Review
- The identification of stem cells in human liver diseases and hepatocellular carcinoma.Experimental and molecular pathology · 2010Article
- Proceedings from the scientific symposium: Sex differences in cardiovascular disease and implications for therapies.Journal of women's health (2002) · 2010Article
- An expanded self-antigen peptidome is carried by the human lymph as compared to the plasma.PloS one · 2010Article
- TLRs, Alcohol, HCV, and Tumorigenesis.Gastroenterology research and practice · 2010Article
- Tissue-derived stem and progenitor cells.Stem cells international · 2010Article
- Adult stem cells and their trans-differentiation potential--perspectives and therapeutic applications.Journal of molecular medicine (Berlin, Germany) · 2008Review
- Recent progress on tissue-resident adult stem cell biology and their therapeutic implications.Stem cell reviews · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Stem cells are undifferentiated cells that can self-renew and generate specialized (functional) cell types. The remarkable ability of stem cells to differentiate towards functional cells makes them suitable modalities in cellular therapy (which means treating diseases with the body's own cells). Potential targets for cellular therapy include diabetes and liver failure. However, in order for stem cells to be clinically useful, we must learn to identify them and to regulate their differentiation. We will use the intestine as a classical example of a stem cell compartment, and then examine the evidence for the existence of adult stem cells in two endodermally derived organs: pancreas and liver. We will review the characteristics of the putative stem cells in these tissues and the transcription factors controlling their differentiation towards functional cell types.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.