ArticleCurrent treatment options in cardiovascular medicine2007
Treatment of chronic venous insufficiency.
Article in Current treatment options in cardiovascular medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 50 citations in OpenAlex.
- Endovenous laser ablation of the great saphenous vein versus high ligation: long-term results.Lasers in medical science · 2014Trial
- Effectiveness of Inspiratory Muscle Training in Individuals with Chronic Venous Disease: A Randomized Controlled Study.Life (Basel, Switzerland) · 2025Article
- Article
- Medical Treatment for Postthrombotic Syndrome.Seminars in interventional radiology · 2017Review
- Venous endothelial injury in central nervous system diseases.BMC medicine · 2013Review
- Evaluation of in vivo antioxidant and immunity enhancing activities of sodium aescinate injection liquid.Molecules (Basel, Switzerland) · 2012Article
- Compression therapy for treatment of venous disease and limb swelling.Current treatment options in cardiovascular medicine · 2011Article
- Endovascular radiofrequency ablation for varicose veins: an evidence-based analysis.Ontario health technology assessment series · 2011Article
- Venous leg ulcerations: a treatment update.Current treatment options in cardiovascular medicine · 2010Article
- Endovascular laser therapy for varicose veins: an evidence-based analysis.Ontario health technology assessment series · 2010Article
- Treatment of varicose veins.Current treatment options in cardiovascular medicine · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic venous insufficiency (CVI) results from venous hypertension secondary to superficial or deep venous valvular reflux. Treatment modalities are aimed at reducing venous valvular reflux, thereby inhibiting the ensuing pathologic inflammatory process. Compression therapy using pumps, bandaging, and/or graded compression stockings is the mainstay of treatment for CVI. Compression therapy has been shown to be effective in reducing venous hypertension retarding the development of inflammation and pathologic skin changes. Pharmacologic agents such as diuretics and topical steroid creams reduce swelling and pain short term but offer no long-term treatment advantage. Herbal supplements may reduce the inflammatory response to venous hypertension, but are not licensed by the US Food and Drug Administration, and vary in their efficacy, quality, and safety. However, several randomized controlled trials using the herbal horse chestnut seed extract containing aescin have shown short-term improvement in signs and symptoms of CVI. Endovascular and surgical techniques aimed at treatment of primary and secondary venous valvular reflux have been shown to improve venous hemodynamics promoting healing of venous ulcers and improving quality of life. The newer endovascular treatments of varicose veins using laser, radiofrequency ablation, and chemical foam sclerotherapy show some promise.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.