ArticleThe Plant cell2007
Arabidopsis protein kinase PKS5 inhibits the plasma membrane H+ -ATPase by preventing interaction with 14-3-3 protein.
Article in The Plant cell, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 199 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
199 citing papers in PubMed, 1 synthesis or guideline pooled it, 441 citations in OpenAlex.
- Root hair growth from the pH point of view.Frontiers in plant science · 2022Pooled it
- CIPK11 Regulates Plant Adaptation to Nitrate Availability in Arabidopsis.Plants (Basel, Switzerland) · 2026Article
- Identification of rice DUF1719 gene family and analysis of alkaline tolerance function of OsDUF1719.8.Functional & integrative genomics · 2026Article
- Tomato NAC2-DREB2 module fine-tunes saline-alkali stress sensitivity via modulation of melatonin biosynthesis and ROS homeostasis.Horticulture research · 2026Article
- A phosphorylation-dependent ubiquitination switch orchestrates nuclear immune reprogramming upon chitin perception.Nature communications · 2026Article
- LjCIPK1: a CBL-interacting protein kinase fromFrontiers in plant science · 2026Article
- TaGF14g, a wheat 14-3-3 protein, acts as a positive regulator of drought and salt tolerance.Plant cell reports · 2025Article
- Spatiotemporal dynamics of AHA2 reveal that RALF1 induces its endocytosis and vacuolar degradation.Plant communications · 2025Article
- Functional 14-3-3 Proteins: Master Regulators in Plant Responses to Salt Stress.Plants (Basel, Switzerland) · 2025Review
- Species-specific phylloplane responses to changes in external pH.Journal of experimental botany · 2025Article
- Harnessing the acid growth theory to optimize apoplastic acidification for enhancing cotton fiber elongation.Plant communications · 2025Article
- Poltergeist-Like 2 (PLL2)-dependent activation of herbivore defence distinguishes systemin from other immune signalling pathways.Nature plants · 2025Article
- Silicon: A valuable soil element for improving plant growth and COJournal of advanced research · 2025Review
- Ethylene increases the NaHCOPlant biotechnology journal · 2025Article
- Plasma membrane HThe Plant journal : for cell and molecular biology · 2025Article
- Molecular tipping points in plant cell surface HQuantitative plant biology · 2025Review
- The Impact of Alkaline Stress on Plant Growth and Its Alkaline Resistance Mechanisms.International journal of molecular sciences · 2024Review
- The brassinosteroid receptor StBRI1 promotes tuber development by enhancing plasma membrane H+-ATPase activity in potato.The Plant cell · 2024Article
- The role of CBL-CIPK signaling in plant responses to biotic and abiotic stresses.Plant molecular biology · 2024Review
- Article
139 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 3 countries.
Funding
Abstract
Regulation of the trans-plasma membrane pH gradient is an important part of plant responses to several hormonal and environmental cues, including auxin, blue light, and fungal elicitors. However, little is known about the signaling components that mediate this regulation. Here, we report that an Arabidopsis thaliana Ser/Thr protein kinase, PKS5, is a negative regulator of the plasma membrane proton pump (PM H+ -ATPase). Loss-of-function pks5 mutant plants are more tolerant of high external pH due to extrusion of protons to the extracellular space. PKS5 phosphorylates the PM H+ -ATPase AHA2 at a novel site, Ser-931, in the C-terminal regulatory domain. Phosphorylation at this site inhibits interaction between the PM H+ -ATPase and an activating 14-3-3 protein in a yeast expression system. We show that PKS5 interacts with the calcium binding protein SCaBP1 and that high external pH can trigger an increase in the concentration of cytosolic-free calcium. These results suggest that PKS5 is part of a calcium-signaling pathway mediating PM H+ -ATPase regulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.