Evidence map›Paper›PMID 17482404›Full record

ReviewExperimental gerontology2007

Telomerase and the aging process.

Peter J Hornsby

Abstract readReview
In one paragraph

Review in Experimental gerontology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
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  7. Review
  8. Review
  9. Review
  10. Aging, Cancer, and Inflammation: The Telomerase Connection.International journal of molecular sciences · 2024
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Peter J HornsbyDepartment of Physiology and Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, TX 78245, USA. hornsby@uthscsa.edu

Funding

STUDIES OF THE MRG15 GENE IN CELL CYCLE AND CELL SENESCENCEP01AG020752 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI SMITH, JAMES · 2001 to 2005
$8.5M
TYPE II 3BETA HSD GENE--REGULATION OF DHEAS SYNTHESISR37AG012287 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI HORNSBY, PETER J · 1998 to 2009
$2.5M
TYPE II 3BETA HSD GENE REGULATION OF DHEAS SYNTHESISR01AG012287 · NIA · BAYLOR COLLEGE OF MEDICINE · PI HORNSBY, PETER J · 1994 to 1997
–
NIA NIH HHS AG12287NIA NIH HHS AG20752NIA NIH HHS P01 AG020752NIA NIH HHS R37 AG012287
6 · The paper itself

Abstract

The level of telomerase activity is important in determining telomere length in aging cells and tissues. Here evidence on the importance of telomerase activity is reviewed with respect to aging rates of mammalian species and the health and life span of individuals within a species. The significance of telomerase reactivation for both cancer development and for immortalizing cells for therapeutic processes is assessed.

Indexed as

AgingAnimalsCell DivisionHealth StatusHumansMammalsTelomeraseTelomerase

Identifiers

PMID17482404
PMCPMC1933587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.