ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2007
Dengue virus evolution and virulence models.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis of all immune epitope data in the Flavivirus genus: inventory of current immune epitope data status in the context of virus immunity and immunopathology.Viral immunology · 2010Pooled it
- Kinetics of viremia and NS1 antigenemia are shaped by immune status and virus serotype in adults with dengue.PLoS neglected tropical diseases · 2011Trial
- Geographic expansion, not viral intensification, leads to human dengue outbreaks in Mexico: a 40-year integrated remote sensing and machine learning analysis.Frontiers in public health · 2026Review
- Article
- Serological Evidence of Flavivirus Infection Among Mothers of Newborns in El Paso, Texas.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2025Article
- A comprehensive and critical narrative review on movement disorders linked through dengue virus based infection.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Review
- Dengue virus surveillance in Nepal yields the first on-site whole genome sequences of isolates from the 2022 outbreak.BMC genomics · 2024Article
- Detection of a Multiple Circulation Event of Dengue Virus 2 Strains in the Northern Region of Brazil.Tropical medicine and infectious disease · 2024Article
- Review
- Article
- Serum biomarkers and anti-flavivirus antibodies at presentation as indicators of severe dengue.PLoS neglected tropical diseases · 2023Article
- Neurological Complications of Dengue Fever.Current neurology and neuroscience reports · 2022Review
- Evolution and epidemiologic dynamics of dengue virus in Nicaragua during the emergence of chikungunya and Zika viruses.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2021Article
- Detection and Genetic Characterization of Puumala Orthohantavirus S-Segment in Areas of France Non-Endemic for Nephropathia Epidemica.Pathogens (Basel, Switzerland) · 2020Article
- Prediction of dengue outbreaks based on disease surveillance, meteorological and socio-economic data.BMC infectious diseases · 2019Article
- Improving Dengue Diagnostics and Management Through Innovative Technology.Current infectious disease reports · 2018Review
- Clinical Efficacy, Safety, and Immunogenicity of a Live Attenuated Tetravalent Dengue Vaccine (CYD-TDV) in Children: A Systematic Review with Meta-analysis.Frontiers in immunology · 2017Review
- Rise and fall of vector infectivity during sequential strain displacements by mosquito-borne dengue virus.Journal of evolutionary biology · 2016Article
- Increasing virulence, but not infectivity, associated with serially emergent virus strains of a fish rhabdovirus.Virus evolution · 2016Article
- Full-length infectious clone of a low passage dengue virus serotype 2 from Brazil.Memorias do Instituto Oswaldo Cruz · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Dengue virus transmission has increased dramatically in the past 2 decades, making this virus one of the most important mosquito-borne human pathogens. The emergence of dengue hemorrhagic fever in most tropical countries has made its control a public health priority, but no vaccines or treatments exist. Little is understood about dengue virus pathogenesis, because no other animals develop symptoms of disease, and research, therefore, has been limited to studies involving patients. Although epidemiologic and evolutionary studies have pointed to host and viral factors in determining disease outcome, only recently developed models could prove the importance of viral genotypes in causing severe epidemics. The influence of host immune status and mosquito vectorial capacity are also being tested in mathematical models to determine virus population dynamics. Therefore, new technologies are allowing us to better understand how specific virus variants cause more disease than others, and these virus variants should be targeted for detection, control, and treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.