ArticleEmerging infectious diseases2007
Meningococcal disease in South Africa, 1999-2002.
Article in Emerging infectious diseases, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Genomic Diversity and Antimicrobial Susceptibility of Invasive Neisseria meningitidis in South Africa, 2016-2021.The Journal of infectious diseases · 2024Article
- Demographic and pathogen characteristics of incident bacterial meningitis in infants in South Africa: A cohort study.PloS one · 2024Article
- Distributed genotyping and clustering of Neisseria strains reveal continual emergence of epidemic meningococcus over a century.Nature communications · 2023Article
- Declining Incidence of Invasive Meningococcal Disease in South Africa: 2003-2016.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Article
- Recent Advances in the Synthesis of Glycoconjugates for Vaccine Development.Molecules (Basel, Switzerland) · 2018Review
- Vaccine prevention of meningococcal disease in Africa: Major advances, remaining challenges.Human vaccines & immunotherapeutics · 2018Review
- Mathematical Modelling of Bacterial Meningitis Transmission Dynamics with Control Measures.Computational and mathematical methods in medicine · 2018Article
- Article
- Fast and accurate dynamic estimation of field effectiveness of meningococcal vaccines.BMC medicine · 2016Article
- Bexsero® chronicle.Pathogens and global health · 2014Review
- Methods of rapid diagnosis for the etiology of meningitis in adults.Biomarkers in medicine · 2014Review
- Clonal analysis of Neisseria meningitidis serogroup B strains in South Africa, 2002 to 2006: emergence of new clone ST-4240/6688.Journal of clinical microbiology · 2012Article
- Importance of circulating antibodies in protection against meningococcal disease.Human vaccines & immunotherapeutics · 2012Review
- Population snapshot of invasive serogroup B meningococci in South Africa from 2005 to 2008.Journal of clinical microbiology · 2012Article
- Complete deficiency of the sixth complement component (C6Q0), susceptibility to Neisseria meningitidis infections and analysis of the frequencies of C6Q0 gene defects in South Africans.Clinical and experimental immunology · 2012Article
- Article
- Genotypic comparison of invasive Neisseria meningitidis serogroup Y isolates from the United States, South Africa, and Israel, isolated from 1999 through 2002.Journal of clinical microbiology · 2009Article
- Neisseria meningitidis intermediately resistant to penicillin and causing invasive disease in South Africa in 2001 to 2005.Journal of clinical microbiology · 2008Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We describe the epidemiology of invasive meningococcal disease in South Africa from August 1999 through July 2002, as reported to a laboratory-based surveillance system. Neisseria meningitidis isolates were further characterized. In total, 854 cases of laboratory-confirmed disease were reported, with an annual incidence rate of 0.64/100,000 population. Incidence was highest in infants < 1 year of age. Serogroup B caused 41% of cases; serogroup A, 23%; serogroup Y, 21%; serogroup C, 8%; and serogroup W135, 5%. Serogroup B was the predominant serogroup in Western Cape Province, and disease rates remained stable. Serogroup A was most prevalent in Gauteng Province and increased over the 3 years. On pulsed-field gel electrophoresis analysis, serogroup A strains showed clonality, and serogroup B demonstrated considerable diversity. Selected isolates of serogroup A belonged to sequence type (ST)-1 (subgroup I/II) complex, serogroup B to ST-32/electrophoretic type (ET)-5 complex, and serogroup W135 to ST-11/ET-37 complex.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.