ArticleThe Journal of physiology2007
Macroendocytosis and endosome processing in snake motor boutons.
Article in The Journal of physiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 40 citations in OpenAlex.
- Uptake and intracellular fate of cholera toxin subunit b-modified mesoporous silica nanoparticle-supported lipid bilayers (aka protocells) in motoneurons.Nanomedicine : nanotechnology, biology, and medicine · 2018Article
- Article
- Visualization of endosome dynamics in living nerve terminals with four-dimensional fluorescence imaging.Journal of visualized experiments : JoVE · 2014Article
- Exocytosis and endocytosis: modes, functions, and coupling mechanisms.Annual review of physiology · 2014Review
- Presynaptic membrane retrieval and endosome biology: defining molecularly heterogeneous synaptic vesicles.Cold Spring Harbor perspectives in biology · 2013Review
- "Late" macroendosomes and acidic endosomes in vertebrate motor nerve terminals.The Journal of comparative neurology · 2012Article
- Synaptic vesicle endocytosis.Cold Spring Harbor perspectives in biology · 2012Review
- Actin- and dynamin-dependent maturation of bulk endocytosis restores neurotransmission following synaptic depletion.PloS one · 2012Article
- Key physiological parameters dictate triggering of activity-dependent bulk endocytosis in hippocampal synapses.PloS one · 2012Article
- Live imaging of bulk endocytosis in frog motor nerve terminals using FM dyes.Journal of neurophysiology · 2011Article
- Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles.Nature neuroscience · 2010Article
- Quantitative monitoring of activity-dependent bulk endocytosis of synaptic vesicle membrane by fluorescent dextran imaging.Journal of neuroscience methods · 2009Article
- Preferred sites of exocytosis and endocytosis colocalize during high- but not lower-frequency stimulation in mouse motor nerve terminals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009Article
- The molecular physiology of activity-dependent bulk endocytosis of synaptic vesicles.Journal of neurochemistry · 2009Review
- The phospho-dependent dynamin-syndapin interaction triggers activity-dependent bulk endocytosis of synaptic vesicles.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009Article
- Activity-dependent bulk synaptic vesicle endocytosis--a fast, high capacity membrane retrieval mechanism.Molecular neurobiology · 2009Review
- The molecular architecture of ribbon presynaptic terminals.Molecular neurobiology · 2009Review
- The spatial pattern of exocytosis and post-exocytic mobility of synaptopHluorin in mouse motor nerve terminals.The Journal of physiology · 2009Article
- Rolling blackout is required for bulk endocytosis in non-neuronal cells and neuronal synapses.Journal of cell science · 2009Article
- Inactivation of clathrin heavy chain inhibits synaptic recycling but allows bulk membrane uptake.The Journal of cell biology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
We have examined the processing of endosomes formed by macroendocytosis (ME), or bulk membrane retrieval, in active motor terminal boutons at the snake nerve-muscle synapse. Endocytic probes were imaged at light (FM1-43) and electron (horseradish peroxidase (HRP)) levels over stimulus frequencies representing low, intermediate and high levels of use. Endosomes formed rapidly (1-2 s) at all frequencies, concomitant with clathrin-mediated vesicular endocytosis (CME). Endosomes dissipated rapidly into vesicles (approximately 10 s). The dissipation rate was not influenced by activity. Many endosomes split into clusters of 2-20 smaller endosomes of varying size. Vesicles budded from these smaller endosomes, from large endosomes that had not undergone fission into smaller ones, and from precursor membrane infoldings that had not yet internalized. In snake, exocytosed vesicular membrane is not competent for reuse until after a delay (> 3 min). We found that time required for endosome processing is not responsible for this delay. Endosome processing might, however, limit availability of some vesicles for release at very high levels of use. Generally, endosome processing paralleled that of vesicles internalized directly from the plasma membrane via CME, regardless of stimulus frequency. There was no evidence for differential recruitment of ME versus CME depending upon level of use.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.