ArticleIrish journal of medical science
Preoperative selection of symptomatic breast cancer patients appropriate for lymphatic mapping and sentinel node biopsy.
Article in Irish journal of medical science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Intraoperative frozen section assessment of sentinel lymph nodes in the operative management of women with symptomatic breast cancer.World journal of surgical oncology · 2008Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study examines whether preoperative ultrasound-assessed tumour diameter and diagnostic core biopsy-determined grade can be used to select those most likely to benefit from SLNB (i.e. those that are "node negative") before their definitive operation.
methodsBreast ultrasound (US) and a simultaneous core biopsy was performed in all patients at their initial presentation, and their estimates of tumor size and grade compared with the final pathological specimen (FPS).
resultsOf the T1 group 47% had lymphatic metastases as did 49% of those with grade I or II cancers. By combining these measures, however, subgroups of patients with lower rates of nodal metastases were identified (32% of patients with T1, non-grade III disease had lymphatic disease while only 15% of those with T < 1.5 cm, non-grade III cancers had such metastases).
conclusionCombination of the US and ultrasound guided core biopsy (UGCB) may however identify subgroups unlikely to have axillary disease that are therefore suitable for SLNB.
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