Evidence map›Paper›PMID 17475763›Full record

ArticleJournal of clinical microbiology2007

Ultrasensitive p24 antigen assay for diagnosis of perinatal human immunodeficiency virus type 1 infection.

Susan A Fiscus, Jeffrey Wiener, Elaine J Abrams, Marc Bulterys, Ada Cachafeiro, Richard A Respess

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Analysis of the optimal cut-point for HIV-p24 antigen testing to diagnose HIV infection in HIV-exposed children from resource-constrained settings.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2011
    Article
  8. Using a simplified human immunodeficiency virus type 1 p24 antigen assay to diagnose pediatric HIV-infection in Malawi.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2010
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Susan A FiscusUniversity of North Carolina at Chapel Hill, Department of Microbiology and Immunology, Chapel Hill, North Carolina, USA. fiscussa@med.unc.edu
Jeffrey Wiener
Elaine J Abrams
Marc Bulterys
Ada Cachafeiro
Richard A Respess
National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention · USUniversity of North Carolina at Chapel Hill · USCenters for Disease Control and Prevention · USColumbia University · US

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
NIAID NIH HHS P30 AI050410NIAID NIH HHS P30 AI50410
6 · The paper itself

Abstract

We evaluated an ultrasensitive p24 antigen enzyme immunosorbent assay on 802 plasma specimens from 582 infants and children of 0 to 180 days of age. Overall sensitivity and specificity were 91.7% and 98.5%, respectively. After exclusion of infants of less than 7 days of age, the sensitivity and specificity were 93.7% and 98.3%, respectively.

Indexed as

Enzyme-Linked Immunosorbent AssayHIV-1HIV Core Protein p24HIV InfectionsHumansInfantInfant, NewbornInfant, Newborn, DiseasesSensitivity and SpecificityUnited StatesHIV Core Protein p24

Identifiers

PMID17475763
PMCPMC1933021
OpenAlexW2104384986

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.