Evidence map›Paper›PMID 17475756›Full record

ArticleJournal of clinical microbiology2007

Detection of mutations conferring resistance to linezolid in Enterococcus spp. by fluorescence in situ hybridization.

Guido Werner, Melanie Bartel, Nele Wellinghausen, Andreas Essig, Ingo Klare, Wolfgang Witte, Sven Poppert

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In one paragraph

Article in Journal of clinical microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Guido WernerInstitute of Medical Microbiology and Hygiene, University Hospital of Ulm, Robert-Kochstr. 8, D-89081 Ulm, Germany.
Melanie Bartel
Nele Wellinghausen
Andreas Essig
Ingo Klare
Wolfgang Witte
Sven Poppert
Institute of Medical Microbiology and Hygiene · DERobert Koch Institute · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A fluorescence in situ hybridization (FISH) assay was established to detect linezolid resistance (conferred by the mutation 2576G>T in the gene coding for the 23 string of the ribosomal RNA) in enterococci. The assay was evaluated with 106 Enterococcus isolates; it showed a sensitivity of 100% for the detection of phenotypic resistance and was even able to identify a single mutated allele in phenotypically linezolid-susceptible isolates.

Indexed as

MutationAcetamidesAnti-Infective AgentsDrug Resistance, BacterialEnterococcusIn Situ Hybridization, FluorescenceLinezolidMicrobial Sensitivity TestsOxazolidinonesRNA, Ribosomal, 23SSensitivity and SpecificityAcetamidesAnti-Infective AgentsLinezolidOxazolidinonesRNA, Ribosomal, 23S

Identifiers

PMID17475756
PMCPMC2045332
OpenAlexW1966932436

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.