ArticleJournal of translational medicine2007
In support of descriptive studies; relevance to translational research.
Article in Journal of translational medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 54 citations in OpenAlex.
- Detailed analysis of immunologic effects of the cytotoxic T lymphocyte-associated antigen 4-blocking monoclonal antibody tremelimumab in peripheral blood of patients with melanoma.Journal of translational medicine · 2008Trial
- Mechanistic Research for the Student or Educator (Part I of II).Frontiers in pharmacology · 2022Article
- Proton Pump Inhibitors and Risk of Incident CKD and Progression to ESRD.Journal of the American Society of Nephrology : JASN · 2016Article
- Oxidative damage and myofiber degeneration in the gastrocnemius of patients with peripheral arterial disease.Journal of translational medicine · 2013Article
- A road map to Translational Medicine in Qatar and a model for the world.Journal of translational medicine · 2012Review
- Social-emotional functioning of children and adolescents with neurofibromatosis type 1 and plexiform neurofibromas: relationships with cognitive, disease, and environmental variables.Journal of pediatric psychology · 2012Article
- Reflections upon human cancer immune responsiveness to T cell-based therapy.Cancer immunology, immunotherapy : CII · 2012Review
- A decade plus of translation: what do we understand?Clinical and translational medicine · 2012Article
- The institutional review board is an impediment to human research: the result is more animal-based research.Philosophy, ethics, and humanities in medicine : PEHM · 2011Article
- Exhaustive expansion: A novel technique for analyzing complex data generated by higher-order polychromatic flow cytometry experiments.Journal of translational medicine · 2010Article
- Translational medicine--doing it backwards.Journal of translational medicine · 2010Article
- Turning laboratory findings into therapy: a marathon goal that has to be reached.Polskie Archiwum Medycyny Wewnetrznej · 2009Review
- Emerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in Oncology.Journal of translational medicine · 2009Article
- AAAS joins the Translational Medicine family.Journal of translational medicine · 2009Article
- New take on comparative immunology: relevance to immunotherapy.Immunotherapy · 2009Article
- Descriptive science.Infection and immunity · 2008Article
- Bottom up: a modular view of immunology.Immunity · 2008Article
- Translational medicine: science or wishful thinking?Journal of translational medicine · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The contemporary scientific establishment equates hypothesis testing to good science. This stance bypasses the preliminary need to identify a worthwhile hypothesis through rigorous observation of natural processes. If alleviation of human suffering is claimed as the goal of a scientific undertaking, it would be unfair to test a hypothesis whose relevance to human disease has not been satisfactorily proven. Here, we argue that descriptive investigations based on direct human observation should be highly valued and regarded essential for the selection of worthwhile hypotheses while the pursuit of costly scientific investigations without such evidence is a desecration of the cause upon which biomedical research is grounded.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.