ReviewCell transplantation2007
Umbilical cord blood research: current and future perspectives.
Review in Cell transplantation, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 72 citations in OpenAlex.
- Human umbilical cord blood-derived mononuclear cell transplantation: case series of 30 subjects with hereditary ataxia.Journal of translational medicine · 2011Trial
- Treatment of refractory non-small cell lung cancer with combined infusion of modified CIK cells and PD1 antibody: safety and efficacy.Clinical and experimental medicine · 2025Article
- Immune composition of the mononuclear cell fraction of human umbilical cord blood.Frontiers in immunology · 2025Article
- Blood-based therapies to combat neurodegenerative diseases.Metabolic brain disease · 2024Review
- Immunoglobulin G passive transfer from mothers to infants: total IgG, IgG subclasses and specific antipneumococcal IgG in 6-week Malawian infants exposed or unexposed to HIV.BMC infectious diseases · 2022Article
- Umbilical cord blood stem cells transplantation in a patient with severe progressive supranuclear palsy: a case report.Journal of medical case reports · 2021Article
- Gender dynamics in the donation field: human tissue donation for research, therapy and feeding.Sociology of health & illness · 2019Article
- Factors Influencing the Umbilical Cord Blood Stem Cell Industry: An Evolving Treatment Landscape.Stem cells translational medicine · 2018Review
- Human Umbilical Cord Blood Serum-derived α-Secretase: Functional Testing in Alzheimer's Disease Mouse Models.Cell transplantation · 2018Article
- Human umbilical cord blood mononuclear cells and chorionic plate-derived mesenchymal stem cells promote axon survival in a rat model of optic nerve crush injury.International journal of molecular medicine · 2016Article
- Neurorestorative Therapy of Stroke in Type 2 Diabetes Mellitus Rats Treated With Human Umbilical Cord Blood Cells.Stroke · 2015Article
- Human umbilical cord blood cells induce neuroprotective change in gene expression profile in neurons after ischemia through activation of Akt pathway.Cell transplantation · 2015Article
- In vitro production of functional immune cells derived from human hematopoietic stem cells.EXCLI journal · 2015Article
- Human cord blood-derived mononuclear cell transplantation for viral encephalitis-associated cognitive impairment: a case report.Journal of medical case reports · 2013Article
- Circulating mononuclear progenitor cells: differential roles for subpopulations in repair of retinal vascular injury.Investigative ophthalmology & visual science · 2013Article
- Protective effects of human umbilical cord blood stem cell intravitreal transplantation against optic nerve injury in rats.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2011Article
- Transplantation of umbilical cord blood stem cells for treating spinal cord injury.Stem cell reviews and reports · 2011Review
- Stem cell-derived islet cells for transplantation.Current opinion in organ transplantation · 2011Review
- Differential macrophage polarization promotes tissue remodeling and repair in a model of ischemic retinopathy.Scientific reports · 2011Article
- Monocyte transplantation for neural and cardiovascular ischemia repair.Journal of cellular and molecular medicine · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Umbilical cord blood (UCB) banking has become a new obstetrical trend. It offers expectant parents a biological insurance policy that can be used in the event of a child or family member's life-threatening illness and puts patients in a position of control over their own treatment options. However, its graduation to conventional therapy in the clinical realm relies on breakthrough research that will prove its efficacy for a range of ailments. Expanding the multipotent cells found within the mononuclear fraction of UCB so that adequate dosing can be achieved, effectively expanding desired cells ex vivo, establishing its safety and limitations in HLA-mismatched recipients, defining its mechanisms of action, and proving its utility in a wide variety of both rare and common illnesses and diseases are a few of the challenges left to tackle. Nevertheless, the field is moving fast and new UCB-based therapies are on the horizon.
Indexed as
Identifiers
17474296PMC2720821W35822870What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.