ArticleJournal of genetic counseling2007
Decision-making about reproductive choices among individuals at-risk for Huntington's disease.
Article in Journal of genetic counseling, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The attitudes of individuals with or at risk of adult-onset genetic conditions on reproductive genetic testing: A systematic review.Journal of genetic counseling · 2025Pooled it
- The Recommendation Paradox: Perspectives on Genetic Testing in Huntington's Disease Families.Journal of genetic counseling · 2026Article
- Patient Perspectives, Unmet Needs and Dilemmas in Reproductive Decision-making for Genodermatoses: A Qualitative Interview Study.Acta dermato-venereologica · 2026Article
- The experience of "at-risk" status for familial frontotemporal dementia (fFTD) and its impact on reproductive decision-making: A qualitative study.Journal of genetic counseling · 2025Article
- Comparison of Patients' Ethical Perspectives of Preimplantation Embryo Genetic Testing for Aneuploidy (PGT-A) vs. Monogenic Disorders (PGT-M).Reproductive sciences (Thousand Oaks, Calif.) · 2021Article
- Perceptions about Research Participation among Individuals at Risk and Individuals with Premanifest Huntington's Disease: A Survey Conducted by the European Huntington Association.Journal of personalized medicine · 2021Article
- Patients' preimplantation genetic testing decision-making experience: an opinion on related psychological frameworks.Human reproduction open · 2019Article
- Ethics in genetic counselling.Journal of community genetics · 2019Review
- "It was an Emotional Baby": Previvors' Family Planning Decision-Making Styles about Hereditary Breast and Ovarian Cancer Risk.Journal of genetic counseling · 2017Article
- A Qualitative Study to Explore the Views and Attitudes towards Prenatal Testing in Adults Who Have Muenke Syndrome and their Partners.Journal of genetic counseling · 2017Article
- At the Heart of the Pregnancy: What Prenatal and Cardiovascular Genetic Counselors Need to Know about Maternal Heart Disease.Journal of genetic counseling · 2017Review
- Toward understanding family-related characteristics of young adults with sickle-cell disease or sickle-cell trait in the USA.Journal of clinical nursing · 2016Article
- Amyotrophic lateral sclerosis in a patient with a family history of huntington disease: genetic counseling challenges.Journal of genetic counseling · 2014Article
- Risk-taking and pathological gambling behavior in Huntington's disease.Frontiers in behavioral neuroscience · 2014Review
- Two decades of Huntington disease testing: patient's demographics and reproductive choices.Journal of genetic counseling · 2013Article
- Psychosocial aspects of preconception consultation in primary care: lessons from our experience in clinical genetics.Journal of community genetics · 2012Article
- Reproductive Decision Making and Genetic Predisposition to Sudden Cardiac Death.AJOB primary research · 2012Article
- Shock, adjust, decide: reproductive decision making in cystic fibrosis (CF) carrier couples--a qualitative study.Journal of genetic counseling · 2011Article
- Quality of Life in Prodromal HD: Qualitative Analyses of Discourse from Participants and Companions.Neurology research international · 2011Article
- What were you thinking?: individuals at risk for Huntington Disease talk about having children.Journal of genetic counseling · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
We explored how individuals at-risk for HD who have or have not been tested make reproductive decisions and what factors are involved. We interviewed 21 individuals (8 with and 4 without the mutation, and 9 un-tested) in-depth for 2 hours each. At-risk individuals faced a difficult series of dilemmas of whether to: get pregnant and deliver, have fetal testing, have pre-implantation genetic diagnosis, adopt, or have no children. These individuals weighed competing desires and concerns: their own desires vs. those of spouses vs. broader moral concerns (e.g., to end the disease; and/or follow dictates against abortion) vs. perceptions of the interests of current or future offspring. Quandaries arose of how much and to whom to feel responsible. Some changed their perspectives over time (e.g., first "gambling," then being more cautious). These data have critical implications for genetic counselors and other health care workers and future research, particularly as more genetic tests become available.
Indexed as
Identifiers
17473962What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.