ReviewBreast disease
Do we need to redefine a cancer metastasis and staging definitions?
Review in Breast disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Connexins in Cancer, the Possible Role of Connexin46 as a Cancer Stem Cell-Determining Protein.Biomolecules · 2023Review
- Targeting tumor innervation: premises, promises, and challenges.Cell death discovery · 2022Review
- Anti-metastatic effect of ranolazine in an in vivo rat model of prostate cancer, and expression of voltage-gated sodium channel protein in human prostate.Prostate cancer and prostatic diseases · 2019Article
- E-Cadherin Downregulation is Mediated by Promoter Methylation in Canine Prostate Cancer.Frontiers in genetics · 2019Article
- The role of vitamin D in hepatic metastases from colorectal cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2018Review
- Coexisting and possible primary extra-gastrointestinal stromal tumors of the pancreas and liver: A single case report.Oncology letters · 2016Article
- Article
- Breast cancer metastasis: issues for the personalization of its prevention and treatment.The American journal of pathology · 2013Review
- Metastasis suppressor genes at the interface between the environment and tumor cell growth.International review of cell and molecular biology · 2011Review
- Specificity and robustness of the mammalian MAPK-IEG network.Biophysical journal · 2009Article
- Inhibition of CXCR4 by CTCE-9908 inhibits breast cancer metastasis to lung and bone.Oncology reports · 2009Article
- Societal interactions in ovarian cancer metastasis: a quorum-sensing hypothesis.Clinical & experimental metastasis · 2009Review
- Dietary stearate reduces human breast cancer metastasis burden in athymic nude mice.Clinical & experimental metastasis · 2009Article
- Metastasis suppressors and the tumor microenvironment.Cancer microenvironment : official journal of the International Cancer Microenvironment Society · 2008Article
- BRMS1 suppresses breast cancer experimental metastasis to multiple organs by inhibiting several steps of the metastatic process.The American journal of pathology · 2008Article
- Metastasis suppressors and their roles in breast carcinoma.Journal of mammary gland biology and neoplasia · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Metastasis is the most lethal attribute of cancer cells and clinical decisions regarding treatment are based largely upon the likelihood of developing metastases. However, improvements in detection as well as recent experimental data have raised questions about the most appropriate definition of a metastasis, especially whether the mere presence of cells at secondary sites constitute a metastatic lesion. After reviewing the experimental basis of metastasis, a definition of metastasis is proffered along with a proposal to consider regarding modification of staging parameters.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.