ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2007
Synthetic protocell biology: from reproduction to computation.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed.
- Template-Based Catalysis and the Emergence of Collectively Autocatalytic Systems.Entropy (Basel, Switzerland) · 2026Article
- Origins of life: the possible and the actual.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Article
- Reconstituting alternative life using the test-bed of cell-free systems.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Fundamental constraints to the logic of living systems.Interface focus · 2024Review
- Multistable Protocells Can Aid the Evolution of Prebiotic Autocatalytic Sets.Life (Basel, Switzerland) · 2023Article
- Article
- From the origin of life to pandemics: emergent phenomena in complex systems.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2022Article
- Ten future challenges for synthetic biology.Engineering biology · 2021Review
- Synthetic Biology: Old and New Dilemmas-The Case of Artificial Life.Biotech (Basel (Switzerland)) · 2021Article
- Asymptotic Information-Theoretic Detection of Dynamical Organization in Complex Systems.Entropy (Basel, Switzerland) · 2021Article
- Investigating the Evolution and Development of Biological Systems from the Perspective of Thermo-Kinetics and Systems Theory.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2020Review
- Dissipative self-assembly, competition and inhibition in a self-reproducing protocell model.Chemical science · 2020Article
- The Origin of a Trans-Generational Organization in the Phenomenon of Biogenesis.Frontiers in physiology · 2019Review
- The evolutionary dynamics of metabolic protocells.PLoS computational biology · 2018Article
- Chemical roots of biological evolution: the origins of life as a process of development of autonomous functional systems.Open biology · 2017Review
- Agent-based models for the emergence and evolution of grammar.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Article
- The major synthetic evolutionary transitions.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Article
- Synthetic transitions: towards a new synthesis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- The RNA World: molecular cooperation at the origins of life.Nature reviews. Genetics · 2015Review
- Toward Spatially Regulated Division of Protocells: Insights into the E. coli Min System from in Vitro Studies.Life (Basel, Switzerland) · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cells are the building blocks of biological complexity. They are complex systems sustained by the coordinated cooperative dynamics of several biochemical networks. Their replication, adaptation and computational features emerge as a consequence of appropriate molecular feedbacks that somehow define what life is. As the last decades have brought the transition from the description-driven biology to the synthesis-driven biology, one great challenge shared by both the fields of bioengineering and the origin of life is to find the appropriate conditions under which living cellular structures can effectively emerge and persist. Here, we review current knowledge (both theoretical and experimental) on possible scenarios of artificial cell design and their future challenges.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.