ArticleGenome biology2007
ngLOC: an n-gram-based Bayesian method for estimating the subcellular proteomes of eukaryotes.
Article in Genome biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 108 citations in OpenAlex.
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- Methods Matter: Standard Production Platforms for Recombinant AAV Produce Chemically and Functionally Distinct Vectors.Molecular therapy. Methods & clinical development · 2020Article
- Characterization of benzimidazole resistance in Haemonchus contortus: integration of phenotypic, genotypic and proteomic approaches.Parasitology research · 2020Article
- Use of Chou's 5-steps rule to predict the subcellular localization of gram-negative and gram-positive bacterial proteins by multi-label learning based on gene ontology annotation and profile alignment.Journal of integrative bioinformatics · 2020Article
- The HCN domain is required for HCN channel cell-surface expression and couples voltage- and cAMP-dependent gating mechanisms.The Journal of biological chemistry · 2020Article
- Assistance for Folding of Disease-Causing Plasma Membrane Proteins.Biomolecules · 2020Review
- A systematic strategy for the investigation of vaccines and drugs targeting bacteria.Computational and structural biotechnology journal · 2020Review
- Athena: Automated Tuning of k-mer based Genomic Error Correction Algorithms using Language Models.Scientific reports · 2019Article
- Chloroplast proteins involved in drought stress response in selected cultivars of common bean (3 Biotech · 2019Article
- Genome-wide characterization of aspartic protease (AP) gene family in Populus trichocarpa and identification of the potential PtAPs involved in wood formation.BMC plant biology · 2019Article
- PSO-LocBact: A Consensus Method for Optimizing Multiple Classifier Results for Predicting the Subcellular Localization of Bacterial Proteins.BioMed research international · 2019Article
- A web-based tool for the prediction of rice transcription factor function.Database : the journal of biological databases and curation · 2019Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present a method called ngLOC, an n-gram-based Bayesian classifier that predicts the localization of a protein sequence over ten distinct subcellular organelles. A tenfold cross-validation result shows an accuracy of 89% for sequences localized to a single organelle, and 82% for those localized to multiple organelles. An enhanced version of ngLOC was developed to estimate the subcellular proteomes of eight eukaryotic organisms: yeast, nematode, fruitfly, mosquito, zebrafish, chicken, mouse, and human.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.