Evidence map›Paper›PMID 17470623›Full record

ReviewThe European respiratory journal2007

Allergen-induced airway remodelling.

C M Lloyd, D S Robinson

Open access · bronzeAbstract readReview
In one paragraph

Review in The European respiratory journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 77 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Frontiers in physiology · 2021
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. On the Move: The Commander IL-4 Leads the Cell Army in Collective Migration.American journal of respiratory cell and molecular biology · 2019
    Article
  10. Review
  11. Journal of immunology research · 2018
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. NK cells in immunotolerant organs.Cellular & molecular immunology · 2013
    Review
  18. Article
  19. Glycyrrhizin and long-term histopathologic changes in a murine model of asthma.Current therapeutic research, clinical and experimental · 2011
    Article
  20. An ovine tracheal explant culture model for allergic airway inflammation.Journal of inflammation (London, England) · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

C M LloydLeukocyte Biology Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, SW7 2AZ, UK. c.lloyd@imperial.ac.uk
D S Robinson
Imperial College London · GB

Funding

Wellcome Trust 057704Wellcome Trust 087618
6 · The paper itself

Abstract

Airway remodelling is associated with chronic asthma but it remains unclear whether it results from airway inflammation in response to allergens or immune-mediated events such as viral infections. Although the acute inflammation associated with asthma has been modelled extensively both in vitro and in vivo, the structural changes occurring in the lung have only recently been investigated. These in vitro, in vivo and in silico systems have been designed to examine the pathways leading to allergen-induced airway remodelling and have enabled investigators to draw conclusions about the participation of key cells and molecules in the development of allergen-induced airway remodelling. However, fundamental questions remain regarding the genesis of remodelling as well as the relationship between functional symptoms and pathological changes that occur. In this review the key questions relating allergen exposure to development of remodelling are discussed, as well as the steps that are being undertaken to investigate them.

Indexed as

AllergensAnimalsAsthmaDisease ProgressionEosinophilsHumansInflammationRespiratory MucosaRespiratory SystemAllergens

Identifiers

PMID17470623
PMCPMC3384680
OpenAlexW2018686087

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.