Evidence map›Paper›PMID 17469833›Full record

ArticleJournal of the American Chemical Society2007

Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster.

Luigi Di Costanzo, Michael E Pique, David W Christianson

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 56 citations in OpenAlex.

  1. Crystal structure of a cold-active arginase from Glaciozyma antarctica.Acta crystallographica. Section F, Structural biology communications · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Characterization of a Dimeric Arginase FromFrontiers in microbiology · 2019
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Arginase-1 deficiency.Journal of molecular medicine (Berlin, Germany) · 2015
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Binding of the unreactive substrate analog L-2-amino-3-guanidinopropionic acid (dinor-L-arginine) to human arginase I.Acta crystallographica. Section F, Structural biology and crystallization communications · 2012
    Article
  18. Article
  19. Article
  20. Crystallization of an apo form of human arginase: using all the tools in the toolbox simultaneously.Acta crystallographica. Section F, Structural biology and crystallization communications · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Luigi Di CostanzoRoy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104-6323, USA.
Michael E Pique
David W Christianson
Scripps Research Institute · USUniversity of Pennsylvania · US

Funding

Structure and Function of MetalloenzymesR01GM049758 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI CHRISTIANSON, DAVID W · 1994 to 2025
$7.6M
NIGMS NIH HHS GM 49758NIGMS NIH HHS R01 GM049758
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ArginaseCrystallography, X-RayHumansLigandsManganeseModels, MolecularProtein Structure, TertiarySemicarbazidesArginaseLigandsManganeseSemicarbazidesthiosemicarbazide

Identifiers

PMID17469833
PMCPMC2593847
OpenAlexW1998357815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.