Evidence map›Paper›PMID 17468941›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2007

Validation of the Migraine-Specific Quality of Life Questionnaire version 2.1 (MSQ v. 2.1) for patients undergoing prophylactic migraine treatment.

Jason C Cole, Peggy Lin, Marcia F T Rupnow

Registry-linked trialAbstract readValidation Study
PubMed Publisher
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03919045 (Saline Injections for Prophylactic Treatment of Chronic Migraine - a Randomized Controlled Study), which is not on this map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03919045 phase4terminatednot on this mapstarted 2019, after this paper: background citation

Saline Injections for Prophylactic Treatment of Chronic Migraine - a Randomized Controlled Study

TypeinterventionalSponsorGöteborg UniversityRan2019 to 2021Enrolled10ConditionsChronic MigraineArmsSaline injection, Placebo
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.

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  18. Acupuncture for migraine prophylaxis: a randomized controlled trial.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2012
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Jason C ColeQualityMetric, 640 George Washington Highway, Suite 201, Lincoln, RI 02865, USA. jcole@qualitymetric.com
Peggy Lin
Marcia F T Rupnow
GroundMetrics (United States) · USJanssen (Belgium) · BEQuality Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHealth-related quality of life (HRQoL) is an important outcome measure of migraine treatments. Although a number of migraine-specific HRQoL questionnaires exist, their measurement characteristics have only been examined for patients undergoing acute treatment of migraine. The goal of the current study was to evaluate measurement properties of the widely used Migraine-Specific Quality of Life Questionnaire version 2.1 (MSQ v. 2.1) within a group of patients undergoing prophylactic migraine treatment.

methodsVarious measurement properties of the MSQ were examined in a sample of 916 migraineurs undergoing prophylactic treatment who had scores at baseline and follow-up, as well as baseline SF-36. First, we used confirmatory factor analysis (CFA) and differential item functioning (DIF) to assure the accuracy and stability across groups of the MSQ scoring for all three subscales (Role Restrictive, Role Preventive, and Emotional Functioning). Next, item- and scale-level properties were examined, such as item-total correlations, internal consistency, and convergent and discriminant validity.

resultsInitial findings revealed that item 12 (measuring frustration on the Emotional Functioning subscale) performed poorly. Subsequent to its removal, the 13-item MSQ displayed excellent measurement properties, including stable latent structure at baseline and endpoint, no gender or age biases on items, appropriate item-level and scale-level reliabilities, and markedly higher convergent validity compared to discriminant validity.

conclusionThe 13-item MSQ appears to be an appropriate measure of migraine-specific HRQoL for patients undergoing migraine prophylaxis. Moreover, given the stability of the latent structure over time, the interpretation of scores is likely to remain quite consistent throughout a clinical trial.

Indexed as

Quality of LifeAdultAnalgesicsFemaleHumansMaleMigraine DisordersPsychometricsReceptors, SerotoninSerotonin Receptor AgonistsSickness Impact ProfileSurveys and QuestionnairesAnalgesicsReceptors, SerotoninSerotonin Receptor Agonists

Identifiers

PMID17468941
OpenAlexW2086980566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.