ReviewCurrent opinion in genetics & development2007
Admixture mapping as a tool in gene discovery.
Review in Current opinion in genetics & development, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Response to: Comment on Genetic Ancestry-Specific Molecular and Survival Differences in Admixed Breast Cancer Patients.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024Article
- Admixture Mapping in African Americans Identifies New Risk Loci for HCV-Related Cirrhosis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023Article
- Ancestral genetic legacy of the extant population of Argentina as predicted by autosomal and X-chromosomal DIPs.Molecular genetics and genomics : MGG · 2021Article
- An Overview of Strategies for Detecting Genotype-Phenotype Associations Across Ancestrally Diverse Populations.Frontiers in genetics · 2021Review
- Article
- Population structure in Argentina.PloS one · 2018Article
- Evidence for a genetic component for substance dependence in Native Americans.The American journal of psychiatry · 2013Review
- Determining ancestry proportions in complex admixture scenarios in South Africa using a novel proxy ancestry selection method.PloS one · 2013Article
- Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production.PLoS genetics · 2013Article
- Human population admixture in Asia.Genomics & informatics · 2012Article
- What are our AIMs? Interdisciplinary Perspectives on the Use of Ancestry Estimation in Disease Research.AJOB primary research · 2012Article
- Genome-wide association identifies multiple genomic regions associated with susceptibility to and control of ovine lentivirus.PloS one · 2012Article
- Comparison of measures of marker informativeness for ancestry and admixture mapping.BMC genomics · 2011Article
- Mathematical properties of Fst between admixed populations and their parental source populations.Theoretical population biology · 2011Article
- New approaches to disease mapping in admixed populations.Nature reviews. Genetics · 2011Review
- Race as a social construct in head and neck cancer outcomes.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2011Article
- Whole-genome genetic diversity in a sample of Australians with deep Aboriginal ancestry.American journal of human genetics · 2010Article
- Genome-wide analysis of the structure of the South African Coloured Population in the Western Cape.Human genetics · 2010Article
- Visualizing chromosome mosaicism and detecting ethnic outliers by the method of "rare" heterozygotes and homozygotes (RHH).Human molecular genetics · 2010Article
- Inferring genetic ancestry: opportunities, challenges, and implications.American journal of human genetics · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Admixture mapping is a rapidly developing method to map susceptibility alleles in complex genetic disease associated with continental ancestry. Theoretically, when admixture between continental populations has occurred relatively recently, the chromosomal segments derived from the parental populations can be deduced from the differences in genotype allele frequencies. Progress in computational algorithms, in identification of ancestry informative single nucleotide polymorphisms, and in recent studies applying these tools suggests that this approach will complement other strategies for identifying the variation that underlies many complex diseases.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.