ArticleCanadian respiratory journal2007
Resource use study in COPD (RUSIC): a prospective study to quantify the effects of COPD exacerbations on health care resource use among COPD patients.
Article in Canadian respiratory journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 5 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Barriers and enablers to centre-based pulmonary rehabilitation for patients with chronic obstructive pulmonary disease in low- and middle-income countries: a systematic review.Journal of global health · 2025Pooled it
- Effectiveness of remote home monitoring for patients with Chronic Obstructive Pulmonary Disease (COPD): systematic review.BMC health services research · 2022Pooled it
- Economic Burden of Chronic Obstructive Pulmonary Disease (COPD): A Systematic Literature Review.International journal of chronic obstructive pulmonary disease · 2020Pooled it
- Clinical, humanistic, and economic burden of chronic obstructive pulmonary disease (COPD) in Canada: a systematic review.BMC research notes · 2015Pooled it
- Exercise prescription for hospitalized people with chronic obstructive pulmonary disease and comorbidities: a synthesis of systematic reviews.International journal of chronic obstructive pulmonary disease · 2012Pooled it
- Assessing the effect of culturally specific audiovisual educational interventions on attaining self-management skills for chronic obstructive pulmonary disease in Mandarin- and Cantonese-speaking patients: a randomized controlled trial.International journal of chronic obstructive pulmonary disease · 2016Trial
- A randomized controlled trial to assess the efficacy of tiotropium in Canadian patients with chronic obstructive pulmonary disease.Canadian respiratory journalTrial
- Preclinical Identification of Poorly Controlled COPD: Patients with a Single Moderate Exacerbation Matter Too.Journal of clinical medicine · 2024Article
- Cost-Effectiveness of Domiciliary High Flow Nasal Cannula Treatment in COPD Patients with Chronic Respiratory Failure.ClinicoEconomics and outcomes research : CEOR · 2021Article
- Management of severe COPD exacerbations: focus on beclomethasone dipropionate/formoterol/glycopyrronium bromide.International journal of chronic obstructive pulmonary disease · 2018Review
- Impact of a COPD comprehensive case management program on hospital length of stay and readmission rates.International journal of chronic obstructive pulmonary disease · 2017Article
- The Burden of Illness Related to Chronic Obstructive Pulmonary Disease Exacerbations in Québec, Canada.Canadian respiratory journal · 2017Observational
- Acute exacerbations of COPD: risk factors for failure and relapse.International journal of chronic obstructive pulmonary disease · 2017Review
- Cost-effectiveness of roflumilast as an add-on treatment to long-acting bronchodilators in the treatment of COPD associated with chronic bronchitis in the United Kingdom.The European journal of health economics : HEPAC : health economics in prevention and care · 2014Article
- Effects of depression diagnosis and antidepressant treatment on mortality in Medicare beneficiaries with chronic obstructive pulmonary disease.Journal of the American Geriatrics Society · 2013Article
- Use of a care bundle in the emergency department for acute exacerbations of chronic obstructive pulmonary disease: a feasibility study.International journal of chronic obstructive pulmonary disease · 2013Article
- Pharmacoeconomic evaluation of tiotropium bromide in the long-term treatment of chronic obstructive pulmonary disease (COPD) in Italy.The European journal of health economics : HEPAC : health economics in prevention and care · 2012Article
- The feasibility and validity of a remote pulse oximetry system for pulmonary rehabilitation: a pilot study.International journal of telemedicine and applications · 2012Article
- Clinical predictors of frequent exacerbations in subjects with severe chronic obstructive pulmonary disease (COPD).Respiratory medicine · 2011Article
- Health literacy, language, and ethnicity-related factors in newcomer asthma patients to Canada: a qualitative study.Journal of immigrant and minority health · 2011Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is increasing interest in health care resource use (HRU) in Canada, particularly in resources associated with acute exacerbations of chronic obstructive pulmonary disease (COPD).
objectiveTo identify HRU due to exacerbations of COPD.
methodsA 52-week, multicentre, prospective, observational study of HRU due to exacerbations in patients with moderate to severe COPD was performed. Patients were recruited from primary care physicians and respirologists in urban and rural centres in Canada.
resultsIn total, 524 subjects (59% men) completed the study. Their mean age was 68.2+/-9.4 years, with a forced expiratory volume in 1 s of 1.01+/-0.4 L. Patients had significant comorbidities. There were 691 acute exacerbations of COPD, which occurred in 53% of patients: 119 patients (23%) experienced one acute exacerbation, 70 patients (13%) had two acute exacerbations and 89 patients (17%) had three or more acute exacerbations. Seventy-five patients were admitted to hospital, with an average length of stay of 13.2 days. Fourteen of the patients spent time in an intensive care unit (average length of stay 5.6 days). Factors associated with acute exacerbations of COPD included lower forced expiratory volume in 1 s (P<0.001), high number of respiratory medications prescribed (P=0.037), regular use of oral corticosteroids (OCSs) (P=0.008) and presence of depression (P<0.001). Of the 75 patients hospitalized, only 53 received OCSs, four received referral for rehabilitation and 15 were referred for home care.
conclusionsThe present study showed a high prevalence of COPD exacerbations, which likely impacted on HRU. There was evidence of a lack of appropriate management of exacerbations, especially with respect to use of OCSs, and referral for pulmonary rehabilitation and home care.
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