Trial reportHIV medicine2007
Multivitamin supplementation in HIV-positive pregnant women: impact on depression and quality of life in a resource-poor setting.
Trial report in HIV medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01614249 (Role of Omega-3 Fish Oil Fatty Acids on Depression Among HIV-seropositive Pregnant Pregnant Women in Nairobi), which is not on this map. Cited by 24 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Role of Omega-3 Fish Oil Fatty Acids on Depression Among HIV-seropositive Pregnant Pregnant Women in Nairobi: A Randomized Double-blind Controlled Trial
Who cites it
24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Vitamin A supplementation during pregnancy for maternal and newborn outcomes.The Cochrane database of systematic reviews · 2015Pooled it
- Dietary supplements for preventing postnatal depression.The Cochrane database of systematic reviews · 2013Pooled it
- Association between vitamin B12 intake and EURRECA's prioritized biomarkers of vitamin B12 in young populations: a systematic review.Public health nutrition · 2013Pooled it
- Micronutrient supplementation in pregnant women with HIV infection.The Cochrane database of systematic reviews · 2012Pooled it
- Understanding modifiable caregiver factors contributing to child development among young children in rural Malawi.Maternal & child nutrition · 2024Trial
- The impact of maternal diet fortification with lipid-based nutrient supplements on postpartum depression in rural Malawi: a randomised-controlled trial.Maternal & child nutrition · 2017Trial
- Sub-optimal vitamin B-12 levels among ART-naïve HIV-positive individuals in an urban cohort in Uganda.PloS one · 2012Trial
- Trial
- Article
- Efficacy and safety of a mineral and vitamin treatment on symptoms of antenatal depression: 12-week fully blinded randomised placebo-controlled trial (NUTRIMUM).BJPsych open · 2024Article
- Prevalence of major depressive disorder and its associated factors among adult patients with neurolathyrism in Dawunt District, Ethiopia; 2022: community-based cross-sectional study.BMC psychiatry · 2024Article
- Inflammation and Vitamin C in Women with Prenatal Depression and Anxiety: Effect of Multinutrient Supplementation.Antioxidants (Basel, Switzerland) · 2023Article
- The pregnancy factor: the prevalence of depression among women living with HIV enrolled in the African Cohort Study (AFRICOS) by pregnancy status.Archives of women's mental health · 2021Article
- Depression and anxiety among pregnant women living with HIV in Kilimanjaro region, Tanzania.PloS one · 2019Article
- Effect of fish oil omega-3 fatty acids on reduction of depressive symptoms among HIV-seropositive pregnant women: a randomized, double-blind controlled trial.Annals of general psychiatry · 2018Article
- Prevalence of prenatal depression and associated factors among HIV-positive women in primary care in Mpumalanga province, South Africa.SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance · 2016Article
- Dietary supplements and disease prevention - a global overview.Nature reviews. Endocrinology · 2016Review
- High perceived social standing is associated with better health in HIV-infected Ugandan adults on highly active antiretroviral therapy.Journal of behavioral medicine · 2016Article
- Article
- Mental health of HIV-seropositive women during pregnancy and postpartum period: a comprehensive literature review.AIDS and behavior · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
Abstract
objectivesThe primary objective of this study was to examine the effect of vitamin supplementation on health-related quality of life and the risk of elevated depressive symptoms comparable to major depressive disorder (MDD) in HIV-positive pregnant women in Dar es Salaam, Tanzania.
methodsFrom April 1995 to July 1997, 1078 HIV-positive pregnant women were enrolled in a randomized controlled trial. We examined the effects of vitamin supplementation on quality of life and the risk of elevated depressive symptoms, assessed longitudinally every 6-12 months.
resultsA substantial prevalence of elevated depressive symptoms (42%) was observed in HIV-positive pregnant women. Multivitamin supplementation (B-complex, C and E) demonstrated a protective effect on depression [relative risk (RR)=0.78; P=0.005] and quality of life [RR=0.72 for social functioning (P=0.001) and vitality (P=0.0001); RR=0.70 for role-physical (P=0.002)]; however, vitamin A showed no effect on these outcomes.
conclusionsMultivitamin supplementation (B-complex, C and E) resulted in a reduction in risk of elevated depressive symptoms comparable to MDD and improvement in quality of life in HIV-positive pregnant women in Tanzania.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.