Evidence map›Paper›PMID 17461454›Full record

ArticleWorld journal of gastroenterology2007

Influence of H pylori on plasma ghrelin in patients without atrophic gastritis.

Mehmet Cindoruk, Ilhan Yetkin, Serpil Muge Deger, Tarkan Karakan, Erdal Kan, Selahattin Unal

Abstract read
In one paragraph

Article in World journal of gastroenterology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Leptin and ghrelin in relation to Helicobacter pylori status in adult males.The Journal of clinical endocrinology and metabolism · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mehmet CindorukGazi University, Department of Gastroenterology, Ankara, Turkey.
Ilhan Yetkin
Serpil Muge Deger
Tarkan Karakan
Erdal Kan
Selahattin Unal
Gazi University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine the association between H pylori infection and serum ghrelin levels in patients without atrophic gastritis.

methodsFifty consecutive patients (24 males and 26 females) with either H pylori-positive gastritis (n = 34) or H pylori-negative gastritis (n = 16) with normal gastric acid secretion determined by 24-h pHmetry and without atrophic gastritis in histopathology were enrolled in this study. Thirty-four H pylori-infected patients were treated with triple therapy consisting of a daily regimen of 30 mg lansoprazole bid, 1 g amoxicillin bid and 500 mg clarithromycin bid for 14 d, followed by an additional 4 wk of 30 mg lansoprazol treatment. H pylori infection was eradicated in 23 of 34 (67.6%) patients. H pylori-positive patients were given eradication therapy. Gastric acidity was determined via intragastric pH catheters. Serum ghrelin was measured by radioimmunoassay (RIA).

resultsThere was no significant difference in plasma ghrelin levels between H pylori-positive and H pylori-negative groups (81.10 +/- 162.66 ng/L vs 76.51 +/- 122.94 ng/L). In addition, there was no significant difference in plasma ghrelin levels and gastric acidity levels measured before and 3 mo after the eradication therapy.

conclusionH pylori infection does not influence ghrelin secretion in patients with chronic gastritis without atrophic gastritis.

Indexed as

2-PyridinylmethylsulfinylbenzimidazolesAdultAmoxicillinAnti-Bacterial AgentsClarithromycinDrug Therapy, CombinationFemaleGastritisGhrelinHelicobacter InfectionsHelicobacter pyloriHumansHydrogen-Ion ConcentrationLansoprazoleMaleMiddle Aged2-PyridinylmethylsulfinylbenzimidazolesAmoxicillinAnti-Bacterial AgentsClarithromycinGhrelinLansoprazolePeptide Hormones

Identifiers

PMID17461454
PMCPMC4146904
OpenAlexW2143109721

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.