ArticleArchives of disease in childhood. Fetal and neonatal edition2007
Nosocomial infection in small for gestational age newborns with birth weight <1500 g: a multicentre analysis.
Article in Archives of disease in childhood. Fetal and neonatal edition, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Association between histamine-2 receptor antagonists and adverse outcomes in neonates: A systematic review and meta-analysis.PloS one · 2019Pooled it
- [Guideline for the diagnosis and treatment of common neonatal diseases in primary healthcare institutions: neonatal infectious pneumonia (2025)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatricsGuideline
- Phenotyping preterm infants at birth to predict infection risk.Pediatric research · 2021Article
- Aberrant Hematopoiesis and Morbidity in Extremely Preterm Infants With Intrauterine Growth Restriction.Frontiers in pediatrics · 2021Article
- Small for gestational age and risk of childhood mortality: A Swedish population study.PLoS medicine · 2018Article
- Treatment and outcome data of very low birth weight infants treated with less invasive surfactant administration in comparison to intubation and mechanical ventilation in the clinical setting of a cross-sectional observational multicenter study.European journal of pediatrics · 2018Observational
- [Incidence of late-onset sepsis in very low birth weight and extremely low birth weight infants and risk factors for late-onset sepsis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2017Article
- Article
- Performance of a Novel Molecular Method in the Diagnosis of Late-Onset Sepsis in Very Low Birth Weight Infants.PloS one · 2015Article
- Role of Neutrophil CD64 Index as a Screening Marker for Late-Onset Sepsis in Very Low Birth Weight Infants.PloS one · 2015Article
- Invasive candidiasis in low birth weight preterm infants: risk factors, clinical course and outcome in a prospective multicenter study of cases and their matched controls.BMC infectious diseases · 2014Article
- Relationship of nosocomial infections with the development of necrotizing enterocolitis in preterm infants.Materia socio-medica · 2014Article
- Trimethoprim-Sulfamethoxazole for Treatment of Stenotrophomonas maltophilia Pneumonia in a Neonate.The Canadian journal of hospital pharmacy · 2013Article
- Late-onset sepsis in very low birth weight infants from singleton and multiple-gestation births.The Journal of pediatrics · 2013Article
- The impact of staffing on central venous catheter-associated bloodstream infections in preterm neonates - results of nation-wide cohort study in Germany.Antimicrobial resistance and infection control · 2013Article
- Inflammation-initiating illnesses, inflammation-related proteins, and cognitive impairment in extremely preterm infants.Brain, behavior, and immunity · 2013Article
- Triazole use in the nursery: fluconazole, voriconazole, posaconazole, and ravuconazole.Current drug metabolism · 2013Review
- The control of invasive Candida infection in very low birth weight infants by reduction in the use of 3rd generation cephalosporin.Korean journal of pediatrics · 2013Article
- Healthcare-associated infections in a neonatal intensive care unit.Archives of medical science : AMS · 2012Article
- Bowel sonography in sepsis with pathological correlation: an experimental study.Pediatric radiology · 2011Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate whether preterm newborns who are small for gestational age are at increased risk of nosocomial infections and necrotising enterocolitis. DESIGN, SETTING AND SUBJECTS: The German national surveillance system for nosocomial infection in very low birthweight infants uses the US Centers for Disease Control and Prevention criteria. 2918 newborns (24-28 weeks), born between 2000 and 2004, were selected after application of predefined inclusion criteria to ensure similar proportions of small and appropriate weight for gestational age newborns across gestational age groups.
main outcome measuresThe outcome criterion was at least one episode of nosocomial sepsis, pneumonia or necrotising enterocolitis. Adjusted odds ratios and corresponding 95% CIs were calculated based on general estimating equation models.
resultsThe study population consisted of 13% (n = 392) small and 87% (n = 2526) appropriate weight for gestational age infants. 33% (n = 950) of the infants experienced at least one episode of sepsis: 42% (n = 163) of small and 31% (n = 787) of appropriate weight for gestational age newborns (adjusted OR 1.41, 95% CI 1.05 to 1.89). Pneumonia was diagnosed in 6% (n = 171) of infants: 8.4% (n = 33) of small and 5.5% (n = 138) of appropriate weight for gestational age newborns (adjusted OR 1.57, 95% CI 1.19 to 5.57). Necrotising enterocolitis was documented in 5.2% (n = 152) of infants: 7.1% (n = 28) of small and 4.9% of (n = 124) appropriate weight for gestational age newborns (adjusted OR 1.20, 95% confidence interval 0.75 to 1.94).
conclusionsGrowth-retarded preterm infants seem to be at increased risk of nosocomial infection, irrespective of the responsible pathogen. Future immunological research should elucidate potential causal associations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.