Evidence map›Paper›PMID 17459775›Full record

ReviewTrends in parasitology2007

Plasmodium malariae and Plasmodium ovale--the "bashful" malaria parasites.

Ivo Mueller, Peter A Zimmerman, John C Reeder

Open access · greenAbstract readReview
In one paragraph

Review in Trends in parasitology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 170 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
170citing papers in PubMed, 3 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

170 citing papers in PubMed, 3 syntheses or guidelines pooled it, 331 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Tropism ofEmerging microbes & infections · 2026
    Article
  6. Article
  7. SubmicroscopicTropical medicine and infectious disease · 2026
    Article
  8. Review
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Review
  14. Unmasking Malaria: Microscopy and nPCR Reveal the Hidden Misdiagnosis ofInterdisciplinary perspectives on infectious diseases · 2026
    Article
  15. Article
  16. Imported plasmodium ovale malaria from Côte d'Ivoire: a case report.Tropical diseases, travel medicine and vaccines · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Analysis of Severe and Relapse Risks of Imported Malaria in Five Provinces of China.The American journal of tropical medicine and hygiene · 2025
    Article

110 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Ivo MuellerPapua New Guinea Institute of Medical Research, Madang MAD511, Papua New Guinea. pngimr_ivo@datec.net.pg
Peter A Zimmerman
John C Reeder
Burnet Institute · AUCenter for Global Health · USPapua New Guinea Institute of Medical Research · PG

Funding

Chloroquine Resistance and pfcrt Variants in PNGR01AI052312 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI ZIMMERMAN, PETER A. · 2002 to 2006
$2.7M
PAPUA NEW GUINEAN DUFFY NEGATIVITY AND VIVAX MALARIAR01AI046919 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI ZIMMERMAN, PETER A. · 2001 to 2005
$2.4M
The effect of mixed Plasmodium infections on morbidityR03AI063135 · NIAID · PAPUA NEW GUINEA INST/ MEDICAL RESEARCH · PI MUELLER, IVO · 2005 to 2006
$103k
NIAID NIH HHS AI 063135NIAID NIH HHS AI 46919NIAID NIH HHS AI 52312NIAID NIH HHS R01 AI046919NIAID NIH HHS R01 AI052312NIAID NIH HHS R03 AI063135
6 · The paper itself

Abstract

Although Plasmodium malariae was first described as an infectious disease of humans by Golgi in 1886 and Plasmodium ovale identified by Stevens in 1922, there are still large gaps in our knowledge of the importance of these infections as causes of malaria in different parts of the world. They have traditionally been thought of as mild illnesses that are caused by rare and, in case of P. ovale, short-lived parasites. However, recent advances in sensitive PCR diagnosis are causing a re-evaluation of this assumption. Low-level infection seems to be common across malaria-endemic areas, often as complex mixed infections. The potential interactions of P. malariae and P. ovale with Plasmodium falciparum and Plasmodium vivax might explain some basic questions of malaria epidemiology, and understanding these interactions could have an important influence on the deployment of interventions such as malaria vaccines.

Indexed as

AdolescentAdultAnimalsChildChild, PreschoolHumansInfantInfant, NewbornMalariaMicroscopyPlasmodium malariaePlasmodium ovalePolymerase Chain ReactionPrevalence

Identifiers

PMID17459775
PMCPMC3728836
OpenAlexW1975097349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.