Evidence map›Paper›PMID 17457341›Full record

ReviewEuropean journal of clinical nutrition2007

Methodology for studying postprandial lipid metabolism.

D Lairon, J Lopez-Miranda, C Williams

Erratum issued Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in European journal of clinical nutrition, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT02079116 (Acute Ingestion of Lipids and Alteration of Cerebral Perfusion in Obese Patients.), which is not on this map. Cited by 55 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02079116 nacompletednot on this mapstarted 2012, after this paper: background citation

Acute Ingestion of Lipids and Alteration of Cerebral Perfusion in Obese Patients.

TypeinterventionalSponsorUniversity of Sao PauloRan2012 to 2014Enrolled20ConditionsObesityArms60 grams of fat plus water solution, Pure water
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

3 authors.

D LaironUMR INSERM 476 Nutrition Humaine et lipides, Faculté de médecine, 27 Bd Jean Moulin, 13385 Marseille Cedex 05, France. denis.lairon@medecine.univ-mrs.fr
J Lopez-Miranda
C Williams

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostprandial lipid metabolism in humans has deserved much attention during the last two decades. Although fasting lipid and lipoprotein parameters reflect body homeostasis to some extent, the transient lipid and lipoprotein accumulation that occurs in the circulation after a fat-containing meal highlights the individual capacity to handle an acute fat input. An exacerbated postprandial accumulation of triglyceride-rich lipoproteins in the circulation has been associated with an increased cardiovascular risk.

methodsThe important number of studies published in this field raises the question of the methodology used for such postprandial studies, as reviewed.

resultsBased on our experiences, the present review reports and discuss the numerous methodological issues involved to serve as a basis for further works. These aspects include aims of the postprandial tests, size and nutrient composition of the test meals and background diets, pre-test conditions, characteristics of subjects involved, timing of sampling, suitable markers of postprandial lipid metabolism and calculations.

conclusionIn conclusion, we stress the need for standardization of postprandial tests.

Indexed as

Area Under CurveBiomarkersDietary FatsHumansLipid MetabolismLipid Metabolism DisordersParticle SizePatient SelectionPostprandial PeriodBiomarkersDietary Fats

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.